Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:SMCE1_HUMAN
Description:SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 [Source:HGNC Symbol;Acc:11109]
Location:chr17 q21.2
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y73KPLMPyMRYSRHMG_boxPhosphoSitePlus
S314EQAERsQSSIVHPRD
T58ASSGItIPKPPPhosphoSitePlus; HPRD
S187YDDGFsMKHTAHPRD
S265LESTDsFNNELPhosphoSitePlus
Y28PGFVGyNPYSHPhosphoSitePlus
Y142PAYLAyINAKSPhosphoSitePlus
S55RVTASsGITIPHPRD
S6MSKRPsYAPPPPhosphoSitePlus
T350THLEEtTESQQPhosphoSitePlus
T17TPAPAtQMPSTPhosphoSitePlus
S157ALEEEsRQRQSPhosphoSitePlus; HPRD
S353EETTEsQQNGEPhosphoSitePlus
Y31VGYNPySHLAYPhosphoSitePlus
S32GYNPYsHLAYNPhosphoSitePlus
S21ATQMPsTPGFVPhosphoSitePlus
T263KFLEStDSFNNPhosphoSitePlus
T363EEGTStPEDKEPhosphoSitePlus; HPRD
T22TQMPStPGFVGPhosphoSitePlus
Y170EKGEPyMSIQPPhosphoSitePlus
S362GEEGTsTPEDKPhosphoSitePlus
Y7SKRPSyAPPPTPhosphoSitePlus
T12YAPPPtPAPATPhosphoSitePlus
Y182EDPDDyDDGFSHPRD
Y139HNSPAyLAYINPhosphoSitePlus

Dephosphorylation site
SMCE1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000323967E261*BIOMARTPancreatic Cancer21930507, 21930502

Differential expressed protein
SMCE1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
SMCE1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
KS6B1_HUMANSMCE1_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
SMCE1_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0003682chromatin bindingTASmolecular_function
GO:0006337nucleosome disassemblyIDAbiological_process
GO:0000228nuclear chromosomeTAScellular_component
GO:0008080N-acetyltransferase activityIDAmolecular_function
GO:0006357regulation of transcription from RNA polymerase IINASbiological_process
GO:0003713transcription coactivator activityNASmolecular_function
GO:0005515protein bindingIPImolecular_function
GO:0016514SWI/SNF complexIEAcellular_component
GO:0003677DNA bindingIEAmolecular_function
GO:0045892negative regulation of transcription, DNA-dependenIDAbiological_process
GO:0006338chromatin remodelingIDAbiological_process
GO:0071565nBAF complexIEAcellular_component
GO:0047485protein N-terminus bindingIPImolecular_function
GO:0005515protein bindingIEAmolecular_function
GO:0017053transcriptional repressor complexIPIcellular_component
GO:0071564npBAF complexIEAcellular_component
GO:0007399nervous system developmentIEAbiological_process
GO:0005634nucleusIDAcellular_component
GO:0016922ligand-dependent nuclear receptor bindingIPImolecular_function


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