Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:SMBT1_HUMAN
Description:Scm-like with four mbt domains 1 [Source:HGNC Symbol;Acc:20255]
Location:chr3 p21.1
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S738EKKSCsSSPTQPhosphoSitePlus
S791RLHLDsNPLKWPhosphoSitePlus
T592VEIVKtADRVTDUF3588PhosphoSitePlus
S765ELRTFsFSDDEPhosphoSitePlus; HPRD; phosphoELM
T452GHPLStPRRARMBTPhosphoSitePlus
T116EQNKKtLEAPEMBTPhosphoSitePlus
Y639KYTHYyGKKKNPhosphoSitePlus
S775ENKPPsPKEIRPhosphoSitePlus; HPRD; phosphoELM
S744SSPTQsEISTSPhosphoSitePlus
S749SEISTsLPPDRPhosphoSitePlus
S451NGHPLsTPRRAMBTPhosphoSitePlus
T407CVATItAVRGSMBTPhosphoSitePlus
T763KRELRtFSFSDPhosphoSitePlus; HPRD
S767RTFSFsDDENKPhosphoSitePlus; HPRD; phosphoELM
Y361FDWADyLKQCGPhosphoSitePlus
T445LGWCEtNGHPLMBTPhosphoSitePlus
S553AAYKPsRVLREDUF3588PhosphoSitePlus
Y105RKADLyPIGWCMBTPhosphoSitePlus

Dephosphorylation site
SMBT1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000378235S412YBIOMARTPancreatic Cancer21930507, 21930502
ENSP00000350789S412YBIOMARTPancreatic Cancer21930507, 21930502
ENSP00000378233E821KCOSMICSkin Cancer21984974
ENSP00000296295S412YBIOMARTPancreatic Cancer21930507, 21930502
ENSP00000378233S412YBIOMARTPancreatic Cancer21930507, 21930502

Differential expressed protein
SMBT1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
SMBT1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
DYRK3_HUMANSMBT1_HUMANkinase -> substrateRobert H Newman (2013)
NEK4_HUMANSMBT1_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
SMBT1_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0006355regulation of transcription, DNA-dependentIEAbiological_process
GO:0005634nucleusIEAcellular_component
GO:0005515protein bindingIEAmolecular_function


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