Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:SIVA_HUMAN
Description:SIVA1, apoptosis-inducing factor [Source:HGNC Symbol;Acc:17712]
Location:chr14 q32.33
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y34VCAERySQEVFAbl2phosphoELM
Y53LGAQAyLDHVWSivaPhosphoSitePlus
Y34VCAERySQEVFABL2RegPhos
Y162DCSDMyEKVLCSivaPhosphoSitePlus
Y34VCAERySQEVFSivaPhosphoSitePlus

Dephosphorylation site
SIVA_HUMAN do not have dephosphorylation site.

Mutation site
SIVA_HUMAN do not have mutation site.

Differential expressed protein
SIVA_HUMAN is not differential expressed protein.

Hyperphosphorylation site
SIVA_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
ABL2_HUMANSIVA_HUMANkinase -> substrateRegPhos; Robert H Newman (2013)

Function Annotation
KEGG Pathway
SIVA_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0006915apoptotic processIEAbiological_process
GO:0019048virus-host interactionIEAbiological_process
GO:0001618viral receptor activityISSmolecular_function
GO:0006924activation-induced cell death of T cellsIDAbiological_process
GO:0005175CD27 receptor bindingIPImolecular_function
GO:0005654nucleoplasmIDAcellular_component
GO:0032088negative regulation of NF-kappaB transcription facIDAbiological_process
GO:0005737cytoplasmIEAcellular_component
GO:0005515protein bindingIPImolecular_function
GO:0009615response to virusISSbiological_process
GO:0005634nucleusIEAcellular_component
GO:0046872metal ion bindingIEAmolecular_function
GO:0008656cysteine-type endopeptidase activator activity invIDAmolecular_function
GO:0006917induction of apoptosisIDAbiological_process
GO:0005739mitochondrionIDAcellular_component
GO:0008635activation of cysteine-type endopeptidase activityIDAbiological_process
GO:0008270zinc ion bindingIDAmolecular_function


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