Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:SIN1_HUMAN
Description:mitogen-activated protein kinase associated protein 1 [Source:HGNC Symbol;Acc:18752]
Location:chr9 q33.3
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S270VEKYSsPGLTSHPRD
S465RRTSFsFQKEKHPRD
T86RRRSNtAQRLESIN1PhosphoSitePlus
S510LNRRTsFSFQKPhosphoSitePlus; HPRD; phosphoELM; SysPTM
S474LNRRTsFSFQKHPRD
S476RRTSFsFQKEKHPRD
S320RRTSFsFQKEKHPRD
S318LNRRTsFSFQKHPRD
Y497TARADyFAQKQPhosphoSitePlus
S463LNRRTsFSFQKHPRD
S270VEKYSsPGLTSSIN1PhosphoSitePlus
S128LFEKKsLKEKPSIN1PhosphoSitePlus
S512RRTSFsFQKEKPhosphoSitePlus; HPRD
S78VEKYSsPGLTSHPRD
S84GIRRRsNTAQRSIN1PhosphoSitePlus

Dephosphorylation site
SIN1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000265961R81TCOSMICOvarian Cancer21720365
ENSP00000265961D376GCOSMICOvarian Cancer21720365

Differential expressed protein
SIN1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
SIN1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
KS6A2_HUMANSIN1_HUMANkinase -> substrateRobert H Newman (2013)
FRK_HUMANSIN1_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
SIN1_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0031295T cell costimulationTASbiological_process
GO:0048015phosphatidylinositol-mediated signalingTASbiological_process
GO:0005634nucleusIEAcellular_component
GO:0016023cytoplasmic membrane-bounded vesicleIEAcellular_component
GO:0005515protein bindingIEAmolecular_function
GO:0007173epidermal growth factor receptor signaling pathwayTASbiological_process
GO:0008150biological_processNDbiological_process
GO:0008543fibroblast growth factor receptor signaling pathwaTASbiological_process
GO:0005886plasma membraneIEAcellular_component
GO:0017016Ras GTPase bindingNASmolecular_function
GO:0005829cytosolTAScellular_component
GO:0016301kinase activityIEAmolecular_function
GO:0048011nerve growth factor receptor signaling pathwayTASbiological_process
GO:0006950response to stressIEAbiological_process


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