| UniProt/SwissProt ID: | SHOX_HUMAN |
| Description: | short stature homeobox [Source:HGNC Symbol;Acc:10853] |
| Location: | chrX p22.33 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S106 | REDVKsEDEDG | PhosphoSitePlus | |
| S120 | LKQRRsRTNFT | Homeobox | PhosphoSitePlus |
| S106 | REDVKsEDEDG | CSNK2A1 | HPRD |
| Y141 | FDETHyPDAFM | Homeobox | PhosphoSitePlus |
| S46 | SGLARsRELGT | PhosphoSitePlus | |
| T125 | SRTNFtLEQLN | Homeobox | PhosphoSitePlus |
| Dephosphorylation site |
| SHOX_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000335505 | *226Y | COSMIC | Ovarian Cancer | 21720365 | ENSP00000370987 | *226Y | COSMIC | Ovarian Cancer | 21720365 | ENSP00000370987 | *226Y | COSMIC | Ovarian Cancer | 21720365 | ENSP00000335505 | *226Y | COSMIC | Ovarian Cancer | 21720365 |
| Differential expressed protein |
| SHOX_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| SHOX_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| CSK21_HUMAN | SHOX_HUMAN | kinase -> substrate | HPRD |
| Function Annotation |
| KEGG Pathway |
| SHOX_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0000976 | transcription regulatory region sequence-specific | IEA | molecular_function |
| GO:0001501 | skeletal system development | TAS | biological_process |
| GO:0006366 | transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0003700 | sequence-specific DNA binding transcription factor | IEA | molecular_function |
| GO:0006355 | regulation of transcription, DNA-dependent | IEA | biological_process |
| GO:0043565 | sequence-specific DNA binding | IEA | molecular_function |
| GO:0005634 | nucleus | IEA | cellular_component |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0005515 | protein binding | IPI | molecular_function |