Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:SF3B4_HUMAN
Description:splicing factor 3b, subunit 4, 49kDa [Source:HGNC Symbol;Acc:10771]
Location:chrHG1287_PATCH q21.
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y56GQHQGyGFVEFRRM_1PhosphoSitePlus
S141PDTGNsKGYAFHPRD
Y69EEDADyAIKIMRRM_1PhosphoSitePlus
Y16QDATVyVGGLDHPRD; phosphoELM
Y16QDATVyVGGLDRRM_1PhosphoSitePlus
S141PDTGNsKGYAFRRM_1PhosphoSitePlus
Y117DEKLLyDTFSAHPRD
Y56GQHQGyGFVEFHPRD; phosphoELM

Dephosphorylation site
SF3B4_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000271628P304SCOSMICOvarian Cancer21720365

Differential expressed protein
SF3B4_HUMAN is not differential expressed protein.

Hyperphosphorylation site
SF3B4_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
MAPK5_HUMANSF3B4_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
SF3B4_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0000375RNA splicing, via transesterification reactionsTASbiological_process
GO:0010467gene expressionTASbiological_process
GO:0005681spliceosomal complexIDAcellular_component
GO:0003723RNA bindingIEAmolecular_function
GO:0008380RNA splicingTASbiological_process
GO:0006397mRNA processingTASbiological_process
GO:0000398mRNA splicing, via spliceosomeICbiological_process
GO:0000166nucleotide bindingIEAmolecular_function
GO:0003676nucleic acid bindingIEAmolecular_function
GO:0005689U12-type spliceosomal complexIDAcellular_component
GO:0005654nucleoplasmTAScellular_component
GO:0005515protein bindingIPImolecular_function


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