| UniProt/SwissProt ID: | SEPT3_HUMAN |
| Description: | septin 3 [Source:HGNC Symbol;Acc:10750] |
| Location: | chr22 q13.2 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S70 | MVVGQsGLGKS | Septin | PhosphoSitePlus |
| S91 | VSRKAsSWNRE | PKG1 | RegPhos |
| S87 | FKSQVsRKASS | Septin | PhosphoSitePlus |
| S91 | VSRKAsSWNRE | PRKG1 | HPRD |
| S84 | NTLFKsQVSRK | Septin | PhosphoSitePlus |
| S92 | SRKASsWNREE | Septin | PhosphoSitePlus |
| S91 | VSRKAsSWNRE | Septin | PhosphoSitePlus |
| S91 | VSRKAsSWNRE | RegPhos | |
| Dephosphorylation site |
| SEPT3_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000379703 | E240K | COSMIC | Skin Cancer | 21984974 | ENSP00000379703 | N318T | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000379704 | N318T | BIOMART | Breast Cancer | 21930507, 21930502 |
| Differential expressed protein |
| SEPT3_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| SEPT3_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| KGP1_HUMAN | SEPT3_HUMAN | kinase -> substrate | HPRD |
| ZAGL2_HUMAN | SEPT3_HUMAN | kinase -> substrate | RegPhos |
| Function Annotation |
| KEGG Pathway |
| SEPT3_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0003674 | molecular_function | ND | molecular_function |
| GO:0045202 | synapse | IEA | cellular_component |
| GO:0000910 | cytokinesis | NAS | biological_process |
| GO:0030054 | cell junction | IEA | cellular_component |
| GO:0003924 | GTPase activity | IEA | molecular_function |
| GO:0031105 | septin complex | IEA | cellular_component |
| GO:0007049 | cell cycle | IEA | biological_process |
| GO:0005525 | GTP binding | IEA | molecular_function |