| UniProt/SwissProt ID: | S10A4_HUMAN |
| Description: | S100 calcium binding protein A4 [Source:HGNC Symbol;Acc:10494] |
| Location: | chr1 q21.3 |
| Node attribute: | gene |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S32 | FKLNKsELKEL | S_100 | PhosphoSitePlus |
| S32 | FKLNKsELKEL | HPRD | |
| Dephosphorylation site |
| S10A4_HUMAN do not have dephosphorylation site. |
| Mutation site |
| S10A4_HUMAN do not have mutation site. |
| Differential expressed protein |
| Ensembl ID | Cancer name | Design | Sample | Change | Ratio | Pubmed |
|---|---|---|---|---|---|---|
| ENSP00000357703 | Hepatocellular Carcinoma | Normal vs. Cancer | cell line | Down | 0.019 | 18646787 | ENSP00000357703 | Hepatocellular Carcinoma | Normal vs. Cancer | cell line | Down | 0.037 | 18646787 | ENSP00000357703 | Gastric Cancer | Cancer vs. Cancer (good vs. proo survival) | tissue | Up | 18830628 | ENSP00000357703 | Pancreatic Cancer | Normal vs. Cancer | tissue | Up | 26 | 19199705 |
| Hyperphosphorylation site |
| S10A4_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| CRTC1_HUMAN | S10A4_HUMAN | TF -> target gene | TRANSFAC |
| Function Annotation |
| KEGG Pathway |
| S10A4_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0042802 | identical protein binding | IEA | molecular_function |
| GO:0005509 | calcium ion binding | IEA | molecular_function |
| GO:0048471 | perinuclear region of cytoplasm | IDA | cellular_component |
| GO:0050786 | RAGE receptor binding | IPI | molecular_function |
| GO:0001837 | epithelial to mesenchymal transition | TAS | biological_process |
| GO:0043123 | positive regulation of I-kappaB kinase/NF-kappaB c | IDA | biological_process |
| GO:0043005 | neuron projection | IEA | cellular_component |
| GO:0048306 | calcium-dependent protein binding | IEA | molecular_function |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0005634 | nucleus | IDA | cellular_component |