Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:CRTC1_HUMAN
Description:CREB regulated transcription coactivator 1 [Source:HGNC Symbol;Acc:16062]
Location:chr19 p13.11
Node attribute:substrate; TF

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S153RTNSDsALHQSPhosphoSitePlus; HPRD
S48LQLQKsQYLQLPhosphoSitePlus
S277LSSSSsTGNLARegPhos
T149TSWRRtNSDSARegPhos
Y61SRGQYyGGSLPphosphoELM
Y50LQKSQyLQLGPPhosphoSitePlus
S172SFSSGsQDVHQPhosphoSitePlus; phosphoELM; RegPhos
S158SALHQsTMTPTPhosphoSitePlus
S86QTPFQsSGLDTRegPhos
S151WRRTNsDSALHNuaK2RegPhos
S169RTNSDsALHQSHPRD
S330ASPTLsPLSPIPhosphoSitePlus
T161HQSTMtPTQPEPhosphoSitePlus; phosphoELM
S139GTMYLsPPADTPhosphoSitePlus; RegPhos
S333TLSPLsPITQAPhosphoSitePlus
S151WRRTNsDSALHPhosphoSitePlus; phosphoELM
S64QYYGGsLPNVNPhosphoSitePlus; RegPhos
S440GIDIAsAPALQRegPhos

Dephosphorylation site
CRTC1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000323332M297ICOSMICSkin Cancer21984974

Differential expressed protein
CRTC1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
CRTC1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
ZAGL2_HUMANCRTC1_HUMANkinase -> substrateRegPhos
CRTC1_HUMANS10A4_HUMANTF -> target geneTRANSFAC
CRTC1_HUMANIL8_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa05166HTLV-I infection

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005515protein bindingIPImolecular_function
GO:0006351transcription, DNA-dependentIEAbiological_process
GO:0032793positive regulation of CREB transcription factor aIEAbiological_process
GO:0005886plasma membraneIDAcellular_component
GO:0005634nucleusIDAcellular_component
GO:0045944positive regulation of transcription from RNA polyIDAbiological_process
GO:0005737cytoplasmIDAcellular_component
GO:0008140cAMP response element binding protein bindingIDAmolecular_function
GO:0019048virus-host interactionIEAbiological_process
GO:0051289protein homotetramerizationIEAbiological_process


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