Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:RPAC1_HUMAN
Description:polymerase (RNA) I polypeptide C, 30kDa [Source:HGNC Symbol;Acc:20194]
Location:chr6 p21.1
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y124PRLFEyRNQGDRNA_pol_L; RNA_pol_A_bacPhosphoSitePlus
Y33DFPGNySGYDDPhosphoSitePlus; HPRD; phosphoELM
S4__MAAsQAVEEPhosphoSitePlus
S254AAEELsRCFSPHPRD
T282NPRLDtFSREIRNA_pol_LPhosphoSitePlus
S34FPGNYsGYDDAPhosphoSitePlus
S226DHAKFsPVATAHPRD
Y36GNYSGyDDAWDPhosphoSitePlus
S284RLDTFsREIFRRNA_pol_LPhosphoSitePlus

Dephosphorylation site
RPAC1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000361465*347CCOSMICOvarian Cancer21720365
ENSP00000361465*347SCOSMICOvarian Cancer21720365

Differential expressed protein
RPAC1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
RPAC1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
CLK2_HUMANRPAC1_HUMANkinase -> substrateRobert H Newman (2013)
FGR_HUMANRPAC1_HUMANkinase -> substrateRobert H Newman (2013)
CDK4_HUMANRPAC1_HUMANkinase -> substrateRobert H Newman (2013)
ST17A_HUMANRPAC1_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
RPAC1_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005654nucleoplasmTAScellular_component
GO:0046983protein dimerization activityIEAmolecular_function
GO:0006360transcription from RNA polymerase I promoterTASbiological_process
GO:0006386termination of RNA polymerase III transcriptionTASbiological_process
GO:0005736DNA-directed RNA polymerase I complexTAScellular_component
GO:0010467gene expressionTASbiological_process
GO:0006363termination of RNA polymerase I transcriptionTASbiological_process
GO:0006351transcription, DNA-dependentIEAbiological_process
GO:0003899DNA-directed RNA polymerase activityIEAmolecular_function
GO:0006385transcription elongation from RNA polymerase III pTASbiological_process
GO:0003677DNA bindingIEAmolecular_function
GO:0006361transcription initiation from RNA polymerase I proTASbiological_process
GO:0006362transcription elongation from RNA polymerase I proTASbiological_process
GO:0006383transcription from RNA polymerase III promoterTASbiological_process


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