Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:RNPS1_HUMAN
Description:RNA binding protein S1, serine-rich domain [Source:HGNC Symbol;Acc:10080]
Location:chr16 p13.3
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T161PSPKPtKVHIGPhosphoSitePlus; phosphoELM; RegPhos
S125SSGSPsPSRRRPhosphoSitePlus; RegPhos; SysPTM
S281SPRRRsPVRRRPhosphoSitePlus; HPRD; phosphoELM; RegPhos
S97GSSSGsSSSSAPhosphoSitePlus
S53ATKESsEKDRGPhosphoSitePlus
S289RRRSRsPGRRRPhosphoSitePlus; HPRD; phosphoELM; RegPhos
S77SSSTRsRSSSTPhosphoSitePlus
T29RAPSPtKRKDRPhosphoSitePlus
S22NNKKSsTRAPSPhosphoSitePlus
S27STRAPsPTKRKPhosphoSitePlus; HPRD; phosphoELM; RegPhos
S10GVKKKsLLGVKPhosphoSitePlus
S35KRKDRsDEKSKPhosphoSitePlus; HPRD
S53ATKESsEKDRGCK2a1(CK2 alphaRegPhos
S81RSRSSsTSSSGPhosphoSitePlus
S94TSTGSsSGSSSPhosphoSitePlus
S141RSRSKsKPPKRPhosphoSitePlus; HPRD
S95STGSSsGSSSSPhosphoSitePlus
S266PMWRRsPPRMRPhosphoSitePlus; phosphoELM; RegPhos
T23NKKSStRAPSPPhosphoSitePlus; HPRD
T91GSSTStGSSSGPhosphoSitePlus
S157KRRSPsPKPTKPhosphoSitePlus; HPRD; phosphoELM; RegPhos
S88SSSGSsTSTGSPhosphoSitePlus
S287PVRRRsRSPGRPhosphoSitePlus; HPRD; phosphoELM; RegPhos
Y205HLSKGyAYVEFHPRD; phosphoELM; RegPhos
S98SSSGSsSSSASPhosphoSitePlus
S85SSTSSsGSSTSPhosphoSitePlus
T82SRSSStSSSGSPhosphoSitePlus
S70RRSASsGSSSTPhosphoSitePlus
S101GSSSSsASSRSPhosphoSitePlus
S182IMEIFsTYGKIHPRD
S87TSSSGsSTSTGPhosphoSitePlus
Y205HLSKGyAYVEFRRM_1PhosphoSitePlus
S104SSSASsRSGSSPhosphoSitePlus
S67TRKRRsASSGSPhosphoSitePlus
S53ATKESsEKDRGCK2_alphaphosphoELM
S155ERKRRsPSPKPPhosphoSitePlus; HPRD; phosphoELM; RegPhos
S251PPRRFsPPRRMPhosphoSitePlus; HPRD; phosphoELM; RegPhos; SysPTM
S90SGSSTsTGSSSPhosphoSitePlus
T89SSGSStSTGSSPhosphoSitePlus
S103SSSSAsSRSGSPhosphoSitePlus
S53ATKESsEKDRGCK2_groupRegPhos
S83RSSSTsSSGSSPhosphoSitePlus
S93STSTGsSSGSSPhosphoSitePlus
S52GATKEsSEKDRHPRD
Y207SKGYAyVEFENRRM_1PhosphoSitePlus

Dephosphorylation site
RNPS1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000380275E232DCOSMICOvarian Cancer21720365
ENSP00000380275E217KCOSMICOvarian Cancer21720365

Differential expressed protein
RNPS1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
RNPS1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
KCC4_HUMANRNPS1_HUMANkinase -> substrateRobert H Newman (2013)
CSK21_HUMANRNPS1_HUMANkinase -> substrateRobert H Newman (2013)
ZAGL2_HUMANRNPS1_HUMANkinase -> substrateRegPhos

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa03015mRNA surveillance pathway
hsa03013RNA transport

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0000184nuclear-transcribed mRNA catabolic process, nonsenIDAbiological_process
GO:0003730mRNA 3'-UTR bindingIDAmolecular_function
GO:0005829cytosolTAScellular_component
GO:0006406mRNA export from nucleusTASbiological_process
GO:0008380RNA splicingTASbiological_process
GO:0006366transcription from RNA polymerase II promoterTASbiological_process
GO:0016071mRNA metabolic processTASbiological_process
GO:0016607nuclear speckIEAcellular_component
GO:0003676nucleic acid bindingIEAmolecular_function
GO:0035145exon-exon junction complexTAScellular_component
GO:0003723RNA bindingTASmolecular_function
GO:0005737cytoplasmIDAcellular_component
GO:0016070RNA metabolic processTASbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0005654nucleoplasmTAScellular_component
GO:0006369termination of RNA polymerase II transcriptionTASbiological_process
GO:0005634nucleusIDAcellular_component
GO:0000166nucleotide bindingIEAmolecular_function
GO:0006351transcription, DNA-dependentTASbiological_process
GO:0000398mRNA splicing, via spliceosomeTASbiological_process
GO:0010467gene expressionTASbiological_process
GO:0031124mRNA 3'-end processingTASbiological_process


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