| UniProt/SwissProt ID: | RNH1_HUMAN |
| Description: | ribonuclease H1 [Source:HGNC Symbol;Acc:18466] |
| Location: | chr2 p25.3 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S76 | VRKSAsPEVSE | HPRD | |
| S22 | PCRRGsRGFGM | PhosphoSitePlus | |
| S74 | AFVRKsASPEV | HPRD | |
| Dephosphorylation site |
| RNH1_HUMAN do not have dephosphorylation site. |
| Mutation site |
| RNH1_HUMAN do not have mutation site. |
| Differential expressed protein |
| RNH1_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| RNH1_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| DYRK4_HUMAN | RNH1_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| MK08_HUMAN | RNH1_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| MK01_HUMAN | RNH1_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| RNH1_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0000287 | magnesium ion binding | IEA | molecular_function |
| GO:0005634 | nucleus | IEA | cellular_component |
| GO:0042803 | protein homodimerization activity | IEA | molecular_function |
| GO:0006401 | RNA catabolic process | TAS | biological_process |
| GO:0004540 | ribonuclease activity | TAS | molecular_function |
| GO:0006264 | mitochondrial DNA replication | IEA | biological_process |
| GO:0005739 | mitochondrion | IEA | cellular_component |
| GO:0004523 | ribonuclease H activity | IEA | molecular_function |
| GO:0003676 | nucleic acid binding | TAS | molecular_function |
| GO:0003723 | RNA binding | TAS | molecular_function |