| UniProt/SwissProt ID: | RND3_HUMAN |
| Description: | Rho family GTPase 3 [Source:HGNC Symbol;Acc:671] |
| Location: | chr2 q23.3 |
| Node attribute: | effector |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T231 | LSAVAtDLRKD | PhosphoSitePlus | |
| S222 | ISHMPsRPELS | PhosphoSitePlus | |
| S7 | KERRAsQKLSS | PhosphoSitePlus | |
| S11 | ASQKLsSKSIM | PhosphoSitePlus | |
| S227 | SRPELsAVATD | PhosphoSitePlus | |
| S218 | ATKRIsHMPSR | PhosphoSitePlus | |
| Dephosphorylation site |
| RND3_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000364886 | R223I | COSMIC | Lung Cancer | 20668451 | ENSP00000263895 | R223I | COSMIC | Lung Cancer | 20668451 |
| Differential expressed protein |
| RND3_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| RND3_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| GBG1_HUMAN | RND3_HUMAN | Gprotein -> effector | gpDB |
| GBG8_HUMAN | RND3_HUMAN | Gprotein -> effector | gpDB |
| GBG5_HUMAN | RND3_HUMAN | Gprotein -> effector | gpDB |
| GBG12_HUMAN | RND3_HUMAN | Gprotein -> effector | gpDB |
| GBG3_HUMAN | RND3_HUMAN | Gprotein -> effector | gpDB |
| GBB2_HUMAN | RND3_HUMAN | Gprotein -> effector | gpDB |
| GBB1_HUMAN | RND3_HUMAN | Gprotein -> effector | gpDB |
| GBB3_HUMAN | RND3_HUMAN | Gprotein -> effector | gpDB |
| GBB5_HUMAN | RND3_HUMAN | Gprotein -> effector | gpDB |
| GBG11_HUMAN | RND3_HUMAN | Gprotein -> effector | gpDB |
| GBG10_HUMAN | RND3_HUMAN | Gprotein -> effector | gpDB |
| GBG2_HUMAN | RND3_HUMAN | Gprotein -> effector | gpDB |
| GBG13_HUMAN | RND3_HUMAN | Gprotein -> effector | gpDB |
| Function Annotation |
| KEGG Pathway |
| RND3_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0003924 | GTPase activity | TAS | molecular_function |
| GO:0030036 | actin cytoskeleton organization | TAS | biological_process |
| GO:0006184 | GTP catabolic process | TAS | biological_process |
| GO:0007264 | small GTPase mediated signal transduction | IEA | biological_process |
| GO:0015031 | protein transport | IEA | biological_process |
| GO:0000139 | Golgi membrane | IEA | cellular_component |
| GO:0007155 | cell adhesion | TAS | biological_process |
| GO:0007165 | signal transduction | IEA | biological_process |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0016020 | membrane | IEA | cellular_component |
| GO:0005622 | intracellular | IEA | cellular_component |