Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:RHG33_HUMAN
Description:Rho GTPase activating protein 33 [Source:HGNC Symbol;Acc:23085]
Location:chr19 q13.12
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T628GSRPDtVTLRSPhosphoSitePlus
Y442YRTLEyLLRHLRhoGAPPhosphoSitePlus
S624PQPSGsRPDTVPhosphoSitePlus
S636LRSAKsEESLSPhosphoSitePlus
T630RPDTVtLRSAKPhosphoSitePlus
T558QGRLGtPTEPTPhosphoSitePlus; HPRD
T552EAQARtQGRLGPhosphoSitePlus; HPRD
S182LSEEAsLNIPAPhosphoSitePlus
T564PTEPTtPKAPAPhosphoSitePlus
S178RRLLLsEEASLPhosphoSitePlus
T560RLGTPtEPTTPPhosphoSitePlus; HPRD
Y406LTYQLyGKFSERhoGAPPhosphoSitePlus
Y406LTYQLyGKFSEFYNHPRD

Dephosphorylation site
RHG33_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000320038P371SCOSMICMelanoma
ENSP00000320038A856VCOSMICHead and Neck Cancer21984974
ENSP00000320038G668SCOSMICOvarian Cancer21720365
ENSP00000320038E441*COSMICHead and Neck Cancer21798893

Differential expressed protein
RHG33_HUMAN is not differential expressed protein.

Hyperphosphorylation site
RHG33_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
FYN_HUMANRHG33_HUMANkinase -> substrateHPRD; RegPhos
ZAGL2_HUMANRHG33_HUMANkinase -> substrateRegPhos

Function Annotation
KEGG Pathway
RHG33_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0007154cell communicationIEAbiological_process
GO:0032321positive regulation of Rho GTPase activityIEAbiological_process
GO:0032855positive regulation of Rac GTPase activityIEAbiological_process
GO:0015031protein transportIEAbiological_process
GO:0030675Rac GTPase activator activityIEAmolecular_function
GO:0005886plasma membraneIEAcellular_component
GO:0005515protein bindingIEAmolecular_function
GO:0007165signal transductionIEAbiological_process
GO:0005100Rho GTPase activator activityIEAmolecular_function
GO:0005515protein bindingIPImolecular_function
GO:0035091phosphatidylinositol bindingIEAmolecular_function
GO:0005737cytoplasmIEAcellular_component
GO:0005622intracellularIEAcellular_component


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