| UniProt/SwissProt ID: | RHBT1_HUMAN |
| Description: | Rho-related BTB domain containing 1 [Source:HGNC Symbol;Acc:18738] |
| Location: | chr10 q21.2 |
| Node attribute: | effector |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T483 | CLSKGtFSDVT | HPRD; phosphoELM | |
| T483 | CLSKGtFSDVT | BTB | PhosphoSitePlus |
| S485 | SKGTFsDVTFK | BTB | PhosphoSitePlus |
| S480 | IKECLsKGTFS | HPRD; phosphoELM | |
| S480 | IKECLsKGTFS | BTB | PhosphoSitePlus |
| S69 | EVLERsRDVVD | Ras | PhosphoSitePlus |
| Dephosphorylation site |
| RHBT1_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000350595 | Y293H | COSMIC | Head and Neck Cancer | 21798897 | ENSP00000338671 | Y293H | COSMIC | Head and Neck Cancer | 21798897 |
| Differential expressed protein |
| RHBT1_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| RHBT1_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| GBB5_HUMAN | RHBT1_HUMAN | Gprotein -> effector | gpDB |
| GBG5_HUMAN | RHBT1_HUMAN | Gprotein -> effector | gpDB |
| GBG11_HUMAN | RHBT1_HUMAN | Gprotein -> effector | gpDB |
| GBB1_HUMAN | RHBT1_HUMAN | Gprotein -> effector | gpDB |
| GBG13_HUMAN | RHBT1_HUMAN | Gprotein -> effector | gpDB |
| GBG8_HUMAN | RHBT1_HUMAN | Gprotein -> effector | gpDB |
| GBG2_HUMAN | RHBT1_HUMAN | Gprotein -> effector | gpDB |
| GBG1_HUMAN | RHBT1_HUMAN | Gprotein -> effector | gpDB |
| GBB2_HUMAN | RHBT1_HUMAN | Gprotein -> effector | gpDB |
| GBB3_HUMAN | RHBT1_HUMAN | Gprotein -> effector | gpDB |
| GBG3_HUMAN | RHBT1_HUMAN | Gprotein -> effector | gpDB |
| GBG12_HUMAN | RHBT1_HUMAN | Gprotein -> effector | gpDB |
| GBG10_HUMAN | RHBT1_HUMAN | Gprotein -> effector | gpDB |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04120 | Ubiquitin mediated proteolysis |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0007165 | signal transduction | IEA | biological_process |
| GO:0005886 | plasma membrane | TAS | cellular_component |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0006184 | GTP catabolic process | IEA | biological_process |
| GO:0016020 | membrane | IEA | cellular_component |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0003924 | GTPase activity | IEA | molecular_function |
| GO:0051056 | regulation of small GTPase mediated signal transdu | TAS | biological_process |
| GO:0005829 | cytosol | TAS | cellular_component |
| GO:0005622 | intracellular | IEA | cellular_component |
| GO:0015031 | protein transport | IEA | biological_process |
| GO:0007264 | small GTPase mediated signal transduction | TAS | biological_process |