| UniProt/SwissProt ID: | RFX2_HUMAN |
| Description: | regulatory factor X, 2 (influences HLA class II expression) [Source:HGNC Symbol;Acc:9983] |
| Location: | chr19 p13.3 |
| Node attribute: | TF |
|
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|
| Y221 | PRSSLyNHYLR | RFX_DNA_binding | PhosphoSitePlus |
| S219 | SLPRSsLYNHY | RFX_DNA_binding | PhosphoSitePlus |
| Y108 | SSTASyFEAPG | RFX1_trans_act | PhosphoSitePlus |
| Y224 | SLYNHyLRHCQ | RFX_DNA_binding | PhosphoSitePlus |
| Y93 | RTAYTyNPEPQ | RFX1_trans_act | PhosphoSitePlus |
| Y287 | QEDTQyMAMRQ | | PhosphoSitePlus |
| Y100 | PEPQMyAPSST | RFX1_trans_act | PhosphoSitePlus |
| Y82 | GGDAVyTNGAI | RFX1_trans_act | PhosphoSitePlus |
| S719 | SDPNHsLQGI_ | | PhosphoSitePlus |
|
RFX2_HUMAN do not have dephosphorylation site.
|
|
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|
| ENSP00000306335 | V549L | COSMIC | Ovarian Cancer | 21720365 |
ENSP00000306335 | E110K | Sjoblom2006, COSMIC, HPI | Breast Cancer | 16959974 | ENSP00000306335 | T189S | COSMIC | Head and Neck Cancer | 21798893 | ENSP00000306335 | A37G | Sjoblom2006, COSMIC, HPI | Breast Cancer | 16959974 |
|
| RFX2_HUMAN is not differential expressed protein. |
|
| RFX2_HUMAN do not have hyperphosphorylation site. |
|
RFX2_HUMAN is not in KEGG pathway.
|
|
| GO ID | GO_Term | Evidence | Ontology |
|---|
| GO:0006355 | regulation of transcription, DNA-dependent | IEA | biological_process |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0006351 | transcription, DNA-dependent | IEA | biological_process |
| GO:0005634 | nucleus | IEA | cellular_component |
|
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Stack trace:
#0 /usr/local/apache/htdocs/PhoSigNet/proteintable.php(435): db_disconnect(Object(mysqli))
#1 {main}
thrown in
/usr/local/apache/htdocs/PhoSigNet/include/locateconfig.inc.php on line
23
