| UniProt/SwissProt ID: | RFX1_HUMAN |
| Description: | regulatory factor X, 1 (influences HLA class II expression) [Source:HGNC Symbol;Acc:9982] |
| Location: | chr19 p13.12 |
| Node attribute: | TF |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S209 | SPPEQsPVQAN | PhosphoSitePlus; HPRD | |
| T164 | SPLQLtNIQVP | HPRD | |
| S776 | INQMLsDLNRV | PhosphoSitePlus | |
| T768 | AVLQNtAQINQ | PhosphoSitePlus | |
| S979 | QALP | HPRD | |
| S978 | VQALPsS____ | PhosphoSitePlus | |
| S514 | LRIKAsSPLLR | PhosphoSitePlus | |
| S204 | TQQVHsPPEQS | PhosphoSitePlus; HPRD | |
| Y888 | DEYMYyLIEHR | PhosphoSitePlus | |
| S515 | RIKASsPLLRL | PhosphoSitePlus | |
| S159 | KPGHVsPLQLT | PhosphoSitePlus; HPRD; SysPTM | |
| S126 | PGSTAsQTGVP | PhosphoSitePlus | |
| T149 | RLLVQtSVQAK | PhosphoSitePlus | |
| Y882 | LIRLLyDEYMY | PhosphoSitePlus | |
| S120 | TVSEAsPGSTA | PhosphoSitePlus; HPRD; phosphoELM; SysPTM | |
| S978 | VQALP | HPRD | |
| T199 | LTVHGtQQVHS | PhosphoSitePlus | |
| S979 | QALPSs_____ | PhosphoSitePlus | |
| T124 | ASPGStASQTG | HPRD; phosphoELM | |
| Dephosphorylation site |
| RFX1_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000254325 | N551T | COSMIC | Ovarian Cancer | 21720365 |
| Differential expressed protein |
| RFX1_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| RFX1_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| RFX1_HUMAN | DQB1_HUMAN | TF -> target gene | TRANSFAC |
| RFX1_HUMAN | PCNA_HUMAN | TF -> target gene | TRANSFAC |
| RFX1_HUMAN | DPA1_HUMAN | TF -> target gene | TRANSFAC |
| RFX1_HUMAN | IL5RA_HUMAN | TF -> target gene | TRANSFAC |
| RFX1_HUMAN | DRA_HUMAN | TF -> target gene | TRANSFAC |
| Function Annotation |
| KEGG Pathway |
| RFX1_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0006955 | immune response | TAS | biological_process |
| GO:0006355 | regulation of transcription, DNA-dependent | IEA | biological_process |
| GO:0003705 | RNA polymerase II distal enhancer sequence-specifi | TAS | molecular_function |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0005634 | nucleus | IEA | cellular_component |