Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:RFFL_HUMAN
Description:ring finger and FYVE-like domain containing E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:24821]
Location:chr17 q12
Node attribute:kinase; ubiquitination(source)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S240PGRRAsLSDLTPhosphoSitePlus; HPRD; phosphoELM; SysPTM
S229TQSIDsEDSFVPhosphoSitePlus; HPRD; phosphoELM; SysPTM
S226EDETQsIDSEDPhosphoSitePlus; HPRD
T150RTRAStLSPDFPhosphoSitePlus
T57AHFANtARKQTPhosphoSitePlus
S152RASTLsPDFPEPhosphoSitePlus
S36NPGYSsFPSPTPhosphoSitePlus
S30RMQAYsNPGYSPhosphoSitePlus
S242RRASLsDLTDLPhosphoSitePlus; HPRD; SysPTM
T245SLSDLtDLEDIPhosphoSitePlus; HPRD; phosphoELM
S149DRTRAsTLSPDPhosphoSitePlus
Y34YSNPGySSFPSPhosphoSitePlus; HPRD; phosphoELM
Y29ARMQAySNPGYPhosphoSitePlus
Y211QEEPVyLESVAPhosphoSitePlus

Dephosphorylation site
RFFL_HUMAN do not have dephosphorylation site.

Mutation site
RFFL_HUMAN do not have mutation site.

Differential expressed protein
RFFL_HUMAN is not differential expressed protein.

Hyperphosphorylation site
RFFL_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
RFFL_HUMANRIPK1_HUMANkinase -> substrateNetPath
RFFL_HUMANRIPK1_HUMANubiquitinationNetPath

Function Annotation
KEGG Pathway
RFFL_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0016020membraneIEAcellular_component
GO:0005737cytoplasmIEAcellular_component
GO:0006915apoptotic processIEAbiological_process
GO:0016023cytoplasmic membrane-bounded vesicleIEAcellular_component
GO:0016567protein ubiquitinationIEAbiological_process
GO:0008270zinc ion bindingIEAmolecular_function
GO:0005515protein bindingIEAmolecular_function
GO:0016874ligase activityIEAmolecular_function
GO:0006886intracellular protein transportIEAbiological_process


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