| UniProt/SwissProt ID: | RBM27_HUMAN |
| Description: | RNA binding motif protein 27 [Source:HGNC Symbol;Acc:29243] |
| Location: | chr5 q32 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| Y146 | GKWRDyDRYYE | PhosphoSitePlus | |
| S120 | KKKYPsPQKTR | PhosphoSitePlus | |
| T513 | FSRTQtQRPNL | PhosphoSitePlus | |
| S566 | RKRAMsGLEGP | PhosphoSitePlus | |
| S1020 | KPKVPsISTET | PhosphoSitePlus; phosphoELM | |
| T477 | SVSSPtPLVPD | PhosphoSitePlus | |
| S769 | HLLNQsGGAGE | PhosphoSitePlus | |
| T796 | SSNLKtPSKLC | PhosphoSitePlus | |
| S475 | HTSVSsPTPLV | PhosphoSitePlus | |
| S884 | ELKTSsAVSTP | PhosphoSitePlus; phosphoELM | |
| T447 | RLQLGtPPPLL | PhosphoSitePlus; phosphoELM; SysPTM | |
| S927 | LRKKLsQLQVE | PhosphoSitePlus | |
| S798 | NLKTPsKLCSG | PhosphoSitePlus | |
| S474 | YHTSVsSPTPL | PhosphoSitePlus | |
| S472 | IGYHTsVSSPT | PhosphoSitePlus | |
| S883 | DELKTsSAVST | PhosphoSitePlus | |
| T471 | SIGYHtSVSSP | phosphoELM | |
| T888 | SSAVStPSKVK | PhosphoSitePlus; phosphoELM | |
| Y741 | QTSGAyVLNKV | PhosphoSitePlus | |
| S128 | KTRSEsSERRT | PhosphoSitePlus | |
| T1023 | VPSIStETEEE | phosphoELM | |
| Y1053 | EDEDEyESRSW | PhosphoSitePlus | |
| S914 | LHKRLsSGEDT | PhosphoSitePlus; phosphoELM | |
| Y789 | HPKMIySSSNL | PhosphoSitePlus | |
| Y77 | LYTKNyLPLLE | PhosphoSitePlus | |
| S887 | TSSAVsTPSKV | PhosphoSitePlus | |
| S792 | MIYSSsNLKTP | PhosphoSitePlus | |
| Dephosphorylation site |
| RBM27_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000265271 | P1019Q | COSMIC | Central Nervous System Neoplasms | 18772396 | ENSP00000265271 | R174* | COSMIC | Pancreatic Cancer | ENSP00000265271 | P782A | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000265271 | S1012* | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000265271 | S1022A | COSMIC | Central Nervous System Neoplasms | 18772396 |
| Differential expressed protein |
| Ensembl ID | Cancer name | Design | Sample | Change | Ratio | Pubmed |
|---|---|---|---|---|---|---|
| ENSP00000265271 | Hepatocellular Carcinoma | Cancer vs. Cancer (HCC vs. HuCCA) | cell line | Up | 20069059 | |
| Hyperphosphorylation site |
| RBM27_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| FRK_HUMAN | RBM27_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| RBM27_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0000166 | nucleotide binding | IEA | molecular_function |
| GO:0006397 | mRNA processing | IEA | biological_process |
| GO:0003676 | nucleic acid binding | IEA | molecular_function |
| GO:0005737 | cytoplasm | IEA | cellular_component |
| GO:0008270 | zinc ion binding | IEA | molecular_function |
| GO:0016607 | nuclear speck | IEA | cellular_component |
| GO:0005634 | nucleus | IDA | cellular_component |