Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:RBM27_HUMAN
Description:RNA binding motif protein 27 [Source:HGNC Symbol;Acc:29243]
Location:chr5 q32
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y146GKWRDyDRYYEPhosphoSitePlus
S120KKKYPsPQKTRPhosphoSitePlus
T513FSRTQtQRPNLPhosphoSitePlus
S566RKRAMsGLEGPPhosphoSitePlus
S1020KPKVPsISTETPhosphoSitePlus; phosphoELM
T477SVSSPtPLVPDPhosphoSitePlus
S769HLLNQsGGAGEPhosphoSitePlus
T796SSNLKtPSKLCPhosphoSitePlus
S475HTSVSsPTPLVPhosphoSitePlus
S884ELKTSsAVSTPPhosphoSitePlus; phosphoELM
T447RLQLGtPPPLLPhosphoSitePlus; phosphoELM; SysPTM
S927LRKKLsQLQVEPhosphoSitePlus
S798NLKTPsKLCSGPhosphoSitePlus
S474YHTSVsSPTPLPhosphoSitePlus
S472IGYHTsVSSPTPhosphoSitePlus
S883DELKTsSAVSTPhosphoSitePlus
T471SIGYHtSVSSPphosphoELM
T888SSAVStPSKVKPhosphoSitePlus; phosphoELM
Y741QTSGAyVLNKVPhosphoSitePlus
S128KTRSEsSERRTPhosphoSitePlus
T1023VPSIStETEEEphosphoELM
Y1053EDEDEyESRSWPhosphoSitePlus
S914LHKRLsSGEDTPhosphoSitePlus; phosphoELM
Y789HPKMIySSSNLPhosphoSitePlus
Y77LYTKNyLPLLEPhosphoSitePlus
S887TSSAVsTPSKVPhosphoSitePlus
S792MIYSSsNLKTPPhosphoSitePlus

Dephosphorylation site
RBM27_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000265271P1019QCOSMICCentral Nervous System Neoplasms18772396
ENSP00000265271R174*COSMICPancreatic Cancer
ENSP00000265271P782ABIOMARTBreast Cancer21930507, 21930502
ENSP00000265271S1012*BIOMARTBreast Cancer21930507, 21930502
ENSP00000265271S1022ACOSMICCentral Nervous System Neoplasms18772396

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000265271Hepatocellular CarcinomaCancer vs. Cancer (HCC vs. HuCCA)cell lineUp20069059

Hyperphosphorylation site
RBM27_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
FRK_HUMANRBM27_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
RBM27_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0003723RNA bindingIEAmolecular_function
GO:0000166nucleotide bindingIEAmolecular_function
GO:0006397mRNA processingIEAbiological_process
GO:0003676nucleic acid bindingIEAmolecular_function
GO:0005737cytoplasmIEAcellular_component
GO:0008270zinc ion bindingIEAmolecular_function
GO:0016607nuclear speckIEAcellular_component
GO:0005634nucleusIDAcellular_component


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