| UniProt/SwissProt ID: | RBM12_HUMAN |
| Description: | RNA binding motif protein 12 [Source:HGNC Symbol;Acc:9898] |
| Location: | chr20 q11.22 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| Y433 | AGFCVyLKGLP | RRM_1 | PhosphoSitePlus |
| S424 | RSRSRsPHEAG | PhosphoSitePlus; HPRD; phosphoELM | |
| S422 | QKRSRsRSPHE | PhosphoSitePlus; HPRD; phosphoELM | |
| S525 | RLQNFsYDQRE | PhosphoSitePlus | |
| S67 | GTIKGsKVTLL | PhosphoSitePlus | |
| T70 | KGSKVtLLLSS | PhosphoSitePlus | |
| T77 | LLSSKtEMQNM | PhosphoSitePlus | |
| Y526 | LQNFSyDQREM | PhosphoSitePlus; HPRD; phosphoELM | |
| S375 | RYVEVsPATER | PhosphoSitePlus; HPRD; SysPTM | |
| S420 | SGQKRsRSRSP | PhosphoSitePlus; HPRD; phosphoELM | |
| S415 | RSKSPsGQKRS | PhosphoSitePlus; HPRD; phosphoELM | |
| S411 | QTLPRsKSPSG | PhosphoSitePlus | |
| T378 | EVSPAtERQWV | PhosphoSitePlus | |
| Y433 | AGFCVyLKGLP | HPRD | |
| T16 | PIVAGtMDIRH | PhosphoSitePlus | |
| Dephosphorylation site |
| RBM12_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000363217 | M395V | COSMIC | Ovarian Cancer | 21720365 | ENSP00000363217 | P782S | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000363217 | E317Q | COSMIC | Head and Neck Cancer | 21798893 | ENSP00000363217 | I205N | COSMIC | Skin Cancer | 21984974 | ENSP00000363217 | A43T | COSMIC | Head and Neck Cancer | 21798893 | ENSP00000352668 | P782S | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000363217 | D355N | COSMIC | Ovarian Cancer | 21720365 | ENSP00000363228 | P782S | BIOMART | Breast Cancer | 21930507, 21930502 |
| Differential expressed protein |
| RBM12_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| RBM12_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| FAK2_HUMAN | RBM12_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| MK14_HUMAN | RBM12_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| CLK2_HUMAN | RBM12_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| ARAF_HUMAN | RBM12_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| RBM12_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0003676 | nucleic acid binding | IEA | molecular_function |
| GO:0005634 | nucleus | IDA | cellular_component |
| GO:0000166 | nucleotide binding | IEA | molecular_function |