| UniProt/SwissProt ID: | RAD9A_HUMAN |
| Description: | RAD9 homolog A (S. pombe) [Source:HGNC Symbol;Acc:9827] |
| Location: | chr11 q13.2 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S336 | PQPPKsPGPHS | CDK1 | phosphoELM |
| T292 | LQAHStPHPDD | PhosphoSitePlus; HPRD; RegPhos | |
| S375 | LAPVRsPQGPS | PhosphoSitePlus; HPRD; phosphoELM; RegPhos | |
| T351 | EAEPStVPGTP | PhosphoSitePlus | |
| S270 | LSDTDsHSQDL | HPRD; phosphoELM | |
| S328 | PSISLsPGPQP | PhosphoSitePlus; HPRD; phosphoELM; RegPhos | |
| Y28 | IGDELyLEPLE | RegPhos | |
| S387 | VLAEDsEG | HPRD; phosphoELM; SysPTM | |
| S254 | FTIKDsLLDGH | Rad9 | PhosphoSitePlus |
| T355 | STVPGtPPPKK | PhosphoSitePlus; HPRD; phosphoELM; RegPhos | |
| S341 | SPGPHsEEEDE | PhosphoSitePlus; HPRD; phosphoELM; RegPhos | |
| S277 | SQDLGsPERHQ | CDK1 | phosphoELM; SysPTM |
| S387 | VLAEDsEGEG_ | PhosphoSitePlus; SysPTM | |
| S277 | SQDLGsPERHQ | PhosphoSitePlus; HPRD; phosphoELM; RegPhos; SysPTM | |
| T167 | ALAEVtLGIGR | Rad9 | PhosphoSitePlus |
| Y28 | IGDELyLEPLE | Rad9 | PhosphoSitePlus |
| S266 | VLATLsDTDSH | HPRD | |
| S387 | VLAEDsEGEG | RegPhos; SysPTM | |
| S324 | SRVLPsISLSP | PhosphoSitePlus | |
| T292 | LQAHStPHPDD | CDK1 | phosphoELM |
| S336 | PQPPKsPGPHS | PhosphoSitePlus; HPRD; phosphoELM; RegPhos | |
| S328 | PSISLsPGPQP | CDK1 | phosphoELM |
| S272 | DTDSHsQDLGS | ATM | HPRD; phosphoELM; RegPhos |
| S328 | PSISLsPGPQP | TLK1 | phosphoELM |
| Y28 | IGDELyLEPLE | Abl | phosphoELM |
| T355 | STVPGtPPPKK | CDK1 | phosphoELM |
| S272 | DTDSHsQDLGS | PhosphoSitePlus; phosphoELM; RegPhos | |
| Y28 | IGDELyLEPLE | ABL1 | HPRD; RegPhos |
| S380 | SPQGPsPVLAE | PhosphoSitePlus; HPRD; phosphoELM; RegPhos | |
| Dephosphorylation site |
| RAD9A_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000311360 | S291N | COSMIC | Head and Neck Cancer | 21984974 |
| Differential expressed protein |
| RAD9A_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| RAD9A_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| ZAGL2_HUMAN | RAD9A_HUMAN | kinase -> substrate | RegPhos |
| ABL1_HUMAN | RAD9A_HUMAN | kinase -> substrate | HPRD; RegPhos |
| ATM_HUMAN | RAD9A_HUMAN | kinase -> substrate | HPRD; RegPhos |
| Function Annotation |
| KEGG Pathway |
| RAD9A_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005634 | nucleus | IEA | cellular_component |
| GO:0005654 | nucleoplasm | TAS | cellular_component |
| GO:0019901 | protein kinase binding | IPI | molecular_function |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0043065 | positive regulation of apoptotic process | IEA | biological_process |
| GO:0000077 | DNA damage checkpoint | IMP | biological_process |
| GO:0000076 | DNA replication checkpoint | TAS | biological_process |
| GO:0042826 | histone deacetylase binding | IPI | molecular_function |
| GO:0006974 | response to DNA damage stimulus | IDA | biological_process |
| GO:0019899 | enzyme binding | IPI | molecular_function |
| GO:0008853 | exodeoxyribonuclease III activity | IEA | molecular_function |
| GO:0017124 | SH3 domain binding | IPI | molecular_function |
| GO:0071479 | cellular response to ionizing radiation | IDA | biological_process |
| GO:0000075 | cell cycle checkpoint | TAS | biological_process |
| GO:0005634 | nucleus | IDA | cellular_component |
| GO:0000075 | cell cycle checkpoint | IEA | biological_process |
| GO:0008408 | 3'-5' exonuclease activity | IDA | molecular_function |
| GO:0005737 | cytoplasm | IEA | cellular_component |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0006281 | DNA repair | IEA | biological_process |
| GO:0006260 | DNA replication | TAS | biological_process |
| GO:0030896 | checkpoint clamp complex | IEA | cellular_component |