Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:RAD9A_HUMAN
Description:RAD9 homolog A (S. pombe) [Source:HGNC Symbol;Acc:9827]
Location:chr11 q13.2
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S336PQPPKsPGPHSCDK1phosphoELM
T292LQAHStPHPDDPhosphoSitePlus; HPRD; RegPhos
S375LAPVRsPQGPSPhosphoSitePlus; HPRD; phosphoELM; RegPhos
T351EAEPStVPGTPPhosphoSitePlus
S270LSDTDsHSQDLHPRD; phosphoELM
S328PSISLsPGPQPPhosphoSitePlus; HPRD; phosphoELM; RegPhos
Y28IGDELyLEPLERegPhos
S387VLAEDsEGHPRD; phosphoELM; SysPTM
S254FTIKDsLLDGHRad9PhosphoSitePlus
T355STVPGtPPPKKPhosphoSitePlus; HPRD; phosphoELM; RegPhos
S341SPGPHsEEEDEPhosphoSitePlus; HPRD; phosphoELM; RegPhos
S277SQDLGsPERHQCDK1phosphoELM; SysPTM
S387VLAEDsEGEG_PhosphoSitePlus; SysPTM
S277SQDLGsPERHQPhosphoSitePlus; HPRD; phosphoELM; RegPhos; SysPTM
T167ALAEVtLGIGRRad9PhosphoSitePlus
Y28IGDELyLEPLERad9PhosphoSitePlus
S266VLATLsDTDSHHPRD
S387VLAEDsEGEGRegPhos; SysPTM
S324SRVLPsISLSPPhosphoSitePlus
T292LQAHStPHPDDCDK1phosphoELM
S336PQPPKsPGPHSPhosphoSitePlus; HPRD; phosphoELM; RegPhos
S328PSISLsPGPQPCDK1phosphoELM
S272DTDSHsQDLGSATMHPRD; phosphoELM; RegPhos
S328PSISLsPGPQPTLK1phosphoELM
Y28IGDELyLEPLEAblphosphoELM
T355STVPGtPPPKKCDK1phosphoELM
S272DTDSHsQDLGSPhosphoSitePlus; phosphoELM; RegPhos
Y28IGDELyLEPLEABL1HPRD; RegPhos
S380SPQGPsPVLAEPhosphoSitePlus; HPRD; phosphoELM; RegPhos

Dephosphorylation site
RAD9A_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000311360S291NCOSMICHead and Neck Cancer21984974

Differential expressed protein
RAD9A_HUMAN is not differential expressed protein.

Hyperphosphorylation site
RAD9A_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
ZAGL2_HUMANRAD9A_HUMANkinase -> substrateRegPhos
ABL1_HUMANRAD9A_HUMANkinase -> substrateHPRD; RegPhos
ATM_HUMANRAD9A_HUMANkinase -> substrateHPRD; RegPhos

Function Annotation
KEGG Pathway
RAD9A_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005634nucleusIEAcellular_component
GO:0005654nucleoplasmTAScellular_component
GO:0019901protein kinase bindingIPImolecular_function
GO:0005515protein bindingIEAmolecular_function
GO:0043065positive regulation of apoptotic processIEAbiological_process
GO:0000077DNA damage checkpointIMPbiological_process
GO:0000076DNA replication checkpointTASbiological_process
GO:0042826histone deacetylase bindingIPImolecular_function
GO:0006974response to DNA damage stimulusIDAbiological_process
GO:0019899enzyme bindingIPImolecular_function
GO:0008853exodeoxyribonuclease III activityIEAmolecular_function
GO:0017124SH3 domain bindingIPImolecular_function
GO:0071479cellular response to ionizing radiationIDAbiological_process
GO:0000075cell cycle checkpointTASbiological_process
GO:0005634nucleusIDAcellular_component
GO:0000075cell cycle checkpointIEAbiological_process
GO:00084083'-5' exonuclease activityIDAmolecular_function
GO:0005737cytoplasmIEAcellular_component
GO:0005515protein bindingIPImolecular_function
GO:0006281DNA repairIEAbiological_process
GO:0006260DNA replicationTASbiological_process
GO:0030896checkpoint clamp complexIEAcellular_component


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