| UniProt/SwissProt ID: | RAD17_HUMAN |
| Description: | RAD17 homolog (S. pombe) [Source:HGNC Symbol;Acc:9807] |
| Location: | chr5 q13.2 |
| Node attribute: | kinase; substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S646 | WSLPLsQNSAS | PhosphoSitePlus | |
| S71 | RGNLSsLEQIY | PhosphoSitePlus | |
| S362 | GMSLKsDAVLS | Rad17 | PhosphoSitePlus |
| S86 | SKEYLsENEPW | Rad17 | PhosphoSitePlus |
| S559 | SELPAsQPQPF | ATR | HPRD |
| S559 | SELPAsQPQPF | ATM | HPRD |
| S81 | YGLENsKEYLS | PhosphoSitePlus | |
| T304 | LNRIVtIEANK | Rad17 | PhosphoSitePlus |
| S367 | SDAVLsKSKRR | Rad17 | PhosphoSitePlus |
| T55 | KNGPStLESSR | PhosphoSitePlus; RegPhos | |
| S335 | SGDIRsAINSL | Rad17; DMA | PhosphoSitePlus |
| S470 | WSLPLsQNSAS | ATM | HPRD |
| S635 | WSLPLsQNSAS | ATR | HPRD |
| S635 | WSLPLsQNSAS | ATM | HPRD |
| S480 | SELPAsQPQPF | ATM | HPRD |
| S480 | SELPAsQPQPF | ATR | HPRD |
| S656 | SELPAsQPQPF | PhosphoSitePlus | |
| S656 | SELPAsQPQPF | ATM | HPRD; phosphoELM; RegPhos |
| S656 | SELPAsQPQPF | ATR | HPRD; RegPhos |
| S646 | WSLPLsQNSAS | ATR | HPRD; RegPhos |
| S549 | WSLPLsQNSAS | ATM | HPRD |
| S549 | WSLPLsQNSAS | ATR | HPRD |
| T293 | LNRIVtIEANK | HPRD | |
| S646 | WSLPLsQNSAS | ATM | HPRD; phosphoELM; RegPhos |
| S359 | RKKGMsLKSDA | Rad17 | PhosphoSitePlus |
| S470 | WSLPLsQNSAS | ATR | HPRD |
| S645 | SELPAsQPQPF | ATM | HPRD |
| S645 | SELPAsQPQPF | ATR | HPRD |
| T128 | LNRIVtIEANK | HPRD | |
| T304 | LNRIVtIEANK | HPRD; RegPhos | |
| T207 | LNRIVtIEANK | HPRD | |
| Dephosphorylation site |
| RAD17_HUMAN do not have dephosphorylation site. |
| Mutation site |
| RAD17_HUMAN do not have mutation site. |
| Differential expressed protein |
| RAD17_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| RAD17_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| ATM_HUMAN | RAD17_HUMAN | kinase -> substrate | RegPhos |
| ZAGL2_HUMAN | RAD17_HUMAN | kinase -> substrate | RegPhos |
| RAD17_HUMAN | ATR_HUMAN | kinase -> substrate | HPRD |
| ATR_HUMAN | RAD17_HUMAN | kinase -> substrate | RegPhos |
| Function Annotation |
| KEGG Pathway |
| RAD17_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0006974 | response to DNA damage stimulus | IEA | biological_process |
| GO:0000076 | DNA replication checkpoint | TAS | biological_process |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0000077 | DNA damage checkpoint | IMP | biological_process |
| GO:0007049 | cell cycle | IEA | biological_process |
| GO:0005634 | nucleus | IEA | cellular_component |
| GO:0042325 | regulation of phosphorylation | IMP | biological_process |
| GO:0005634 | nucleus | IDA | cellular_component |
| GO:0007093 | mitotic cell cycle checkpoint | IMP | biological_process |
| GO:0000781 | chromosome, telomeric region | IDA | cellular_component |
| GO:0006260 | DNA replication | TAS | biological_process |
| GO:0005654 | nucleoplasm | TAS | cellular_component |
| GO:0017111 | nucleoside-triphosphatase activity | IEA | molecular_function |
| GO:0008156 | negative regulation of DNA replication | IMP | biological_process |
| GO:0000075 | cell cycle checkpoint | TAS | biological_process |
| GO:0006281 | DNA repair | IEA | biological_process |