| UniProt/SwissProt ID: | R3HD2_HUMAN |
| Description: | R3H domain containing 2 [Source:HGNC Symbol;Acc:29167] |
| Location: | chr12 q13.3 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| Y146 | DSSQEyTDSTG | PhosphoSitePlus | |
| T453 | SRQGStEAADP | PhosphoSitePlus | |
| T316 | SRQSStDSELK | PhosphoSitePlus | |
| S853 | RQALKsASTDL | PhosphoSitePlus; HPRD; phosphoELM | |
| T872 | RVLEVtDLPEG | PhosphoSitePlus | |
| S143 | LSRDSsQEYTD | PhosphoSitePlus; phosphoELM | |
| Y930 | DLAALyTIVAV | PhosphoSitePlus | |
| T879 | LPEGItRTEAD | PhosphoSitePlus | |
| S315 | SSRQSsTDSEL | PhosphoSitePlus | |
| T357 | GISILtRGDSI | PhosphoSitePlus | |
| S351 | KASSFsGISIL | PhosphoSitePlus | |
| S142 | MLSRDsSQEYT | PhosphoSitePlus | |
| T147 | SSQEYtDSTGI | PhosphoSitePlus | |
| S314 | SSSRQsSTDSE | PhosphoSitePlus | |
| S349 | VTKASsFSGIS | PhosphoSitePlus; HPRD | |
| T860 | STDLGtADVVL | PhosphoSitePlus | |
| S365 | DSIGSsKGGSA | PhosphoSitePlus | |
| S361 | LTRGDsIGSSK | PhosphoSitePlus | |
| S452 | LSRQGsTEAAD | PhosphoSitePlus | |
| S310 | LSRTSsSRQSS | PhosphoSitePlus | |
| S139 | PRKMLsRDSSQ | PhosphoSitePlus | |
| S855 | ALKSAsTDLGT | PhosphoSitePlus; HPRD | |
| S348 | PVTKAsSFSGI | PhosphoSitePlus | |
| Dephosphorylation site |
| R3HD2_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000317903 | K34N | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000317903 | P719T | BIOMART | Pancreatic Cancer | 21930507, 21930502 | ENSP00000351784 | K34N | BIOMART | Breast Cancer | 21930507, 21930502 |
| Differential expressed protein |
| R3HD2_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| R3HD2_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| ST17A_HUMAN | R3HD2_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| PIM2_HUMAN | R3HD2_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| R3HD2_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0003676 | nucleic acid binding | IEA | molecular_function |
| GO:0005634 | nucleus | IEA | cellular_component |