Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:PTSS1_HUMAN
Description:phosphatidylserine synthase 1 [Source:HGNC Symbol;Acc:9587]
Location:chr8 q22.1
Node attribute:ligand

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y416HREKTySECEDPhosphoSitePlus; HPRD
S454NNESHsSRRRNPhosphoSitePlus; HPRD; SysPTM
S455NESHSsRRRNRPhosphoSitePlus; HPRD; phosphoELM
T415GHREKtYSECEPhosphoSitePlus; HPRD
S3___MAsCVGSRPhosphoSitePlus
S11GSRTLsKDDVNPhosphoSitePlus; HPRD
S417REKTYsECEDGPhosphoSitePlus; HPRD; phosphoELM; SysPTM
Y424CEDGTySPEISPhosphoSitePlus; phosphoELM
S442KGSEDsPPKHAPhosphoSitePlus; HPRD; SysPTM
S7ASCVGsRTLSKPhosphoSitePlus
S462RRNRHsKSKVTPhosphoSitePlus
Y17KDDVNyKMHFRPhosphoSitePlus
T436HHRKGtKGSEDPhosphoSitePlus
T423ECEDGtYSPEIPhosphoSitePlus; HPRD
S425EDGTYsPEISWPhosphoSitePlus; HPRD; phosphoELM; SysPTM

Dephosphorylation site
PTSS1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000430548H411QTCGAOvarian Cancer21720365, 18772890
ENSP00000430548*474GCOSMICOvarian Cancer21720365

Differential expressed protein
PTSS1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
PTSS1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
PTSS1_HUMANSCRB1_HUMANligand -> receptorHPMR
PTSS1_HUMANJMJD6_HUMANligand -> receptorHPMR

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa01100Metabolic pathways
hsa00564Glycerophospholipid metabolism

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0016021integral to membraneIEAcellular_component
GO:0016020membraneISScellular_component
GO:0006644phospholipid metabolic processTASbiological_process
GO:0046474glycerophospholipid biosynthetic processTASbiological_process
GO:0016740transferase activityIEAmolecular_function
GO:0005789endoplasmic reticulum membraneIEAcellular_component
GO:0044281small molecule metabolic processTASbiological_process
GO:0006659phosphatidylserine biosynthetic processIEAbiological_process


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