Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:JMJD6_HUMAN
Description:jumonji domain containing 6 [Source:HGNC Symbol;Acc:19355]
Location:chr17 q25.1
Node attribute:receptor

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S350DSSSSsSSSSSPhosphoSitePlus
S23PELKDsLDWTRPhosphoSitePlus
Y108EDNDGySVKMKPhosphoSitePlus
S401SKERSsSR___PhosphoSitePlus
T379RKKRRtCSMVGPhosphoSitePlus
S390NGDTTsQDDCVPhosphoSitePlus
S400VSKERsSSR__PhosphoSitePlus
S351SSSSSsSSSSDPhosphoSitePlus
S135LYIFDsSYGEHHPRD
S396QDDCVsKERSSPhosphoSitePlus
S349SDSSSsSSSSSPhosphoSitePlus
S381KRRTCsMVGNGPhosphoSitePlus
S402KERSSsR____PhosphoSitePlus
S348SSDSSsSSSSSPhosphoSitePlus

Dephosphorylation site
JMJD6_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000380750R8SCOSMICOvarian Cancer21720365
ENSP00000380750*404SCOSMICCentral Nervous System Neoplasms10560660
ENSP00000380750N293DCOSMICMelanoma21499247
ENSP00000380750R62LCOSMICOvarian Cancer21720365
ENSP00000380750Q259KCOSMICMelanoma21499247

Differential expressed protein
JMJD6_HUMAN is not differential expressed protein.

Hyperphosphorylation site
JMJD6_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
PTSS1_HUMANJMJD6_HUMANligand -> receptorHPMR

Function Annotation
KEGG Pathway
JMJD6_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0001568blood vessel developmentIEAbiological_process
GO:0005886plasma membraneIEAcellular_component
GO:0005506iron ion bindingIDAmolecular_function
GO:0048024regulation of mRNA splicing, via spliceosomeIEAbiological_process
GO:0070079histone H4-R3 demethylationIDAbiological_process
GO:0001822kidney developmentIEAbiological_process
GO:0070078histone H3-R2 demethylationIDAbiological_process
GO:0048821erythrocyte developmentIEAbiological_process
GO:0002040sprouting angiogenesisIEAbiological_process
GO:0030324lung developmentIEAbiological_process
GO:0048024regulation of mRNA splicing, via spliceosomeIMPbiological_process
GO:0006397mRNA processingIEAbiological_process
GO:0018395peptidyl-lysine hydroxylation to 5-hydroxy-L-lysinIDAbiological_process
GO:0006355regulation of transcription, DNA-dependentIEAbiological_process
GO:0006915apoptotic processIEAbiological_process
GO:0003727single-stranded RNA bindingIDAmolecular_function
GO:0042116macrophage activationIEAbiological_process
GO:0016702oxidoreductase activity, acting on single donors wIEAmolecular_function
GO:0070815peptidyl-lysine 5-dioxygenase activityIDAmolecular_function
GO:0005634nucleusIDAcellular_component
GO:0043277apoptotic cell clearanceIEAbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0033077T cell differentiation in thymusIEAbiological_process
GO:0005634nucleusIEAcellular_component
GO:0005730nucleolusIDAcellular_component
GO:0004872receptor activityIEAmolecular_function
GO:0005654nucleoplasmIDAcellular_component
GO:0003723RNA bindingTASmolecular_function
GO:0033746histone demethylase activity (H3-R2 specific)IDAmolecular_function
GO:0033749histone demethylase activity (H4-R3 specific)IDAmolecular_function
GO:0008380RNA splicingIEAbiological_process
GO:0043654recognition of apoptotic cellIEAbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0042802identical protein bindingIDAmolecular_function
GO:0002040sprouting angiogenesisISSbiological_process
GO:0007166cell surface receptor signaling pathwayIEAbiological_process
GO:0007507heart developmentIEAbiological_process
GO:0060041retina development in camera-type eyeIEAbiological_process
GO:0006351transcription, DNA-dependentIEAbiological_process