Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:PTPS_HUMAN
Description:6-pyruvoyltetrahydropterin synthase [Source:HGNC Symbol;Acc:9689]
Location:chr11 q23.1
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S23ISFSAsHRLYSHPRD
S19VSRRIsFSASHPKG2RegPhos; SysPTM
S19VSRRIsFSASHHPRD; phosphoELM; SysPTM
S19VSRRIsFSASHPRKG2HPRD; SysPTM
S19VSRRIsFSASHPKG_groupRegPhos; SysPTM
S21RRISFsASHRLHPRD
Y128PVGVLyKVKVYPTPSPhosphoSitePlus
S19VSRRIsFSASHPTPSPhosphoSitePlus; SysPTM

Dephosphorylation site
PTPS_HUMAN do not have dephosphorylation site.

Mutation site
PTPS_HUMAN do not have mutation site.

Differential expressed protein
PTPS_HUMAN is not differential expressed protein.

Hyperphosphorylation site
PTPS_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
KGP2_HUMANPTPS_HUMANkinase -> substrateHPRD

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa00790Folate biosynthesis
hsa01100Metabolic pathways

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0042803protein homodimerization activityIEAmolecular_function
GO:0046209nitric oxide metabolic processTASbiological_process
GO:0005829cytosolTAScellular_component
GO:0005737cytoplasmIDAcellular_component
GO:0044281small molecule metabolic processTASbiological_process
GO:0050999regulation of nitric-oxide synthase activityTASbiological_process
GO:00038746-pyruvoyltetrahydropterin synthase activityIEAmolecular_function
GO:0042802identical protein bindingIPImolecular_function
GO:0006729tetrahydrobiopterin biosynthetic processIEAbiological_process
GO:0046872metal ion bindingIEAmolecular_function
GO:0005515protein bindingIEAmolecular_function
GO:0042802identical protein bindingIEAmolecular_function
GO:0007417central nervous system developmentTASbiological_process
GO:0006520cellular amino acid metabolic processTASbiological_process
GO:0005739mitochondrionIEAcellular_component


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