Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:PTN5_HUMAN
Description:protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched) [Source:HGNC Symbol;Acc:9657]
Location:chr11 p15.1
Node attribute:phosphotase

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S66PPSPPsDPAQKPhosphoSitePlus
T255TLDMCtPGCNEPhosphoSitePlus
S444LISLKsGTEERY_phosphatasePhosphoSitePlus
S245QERRGsNVSLTPhosphoSitePlus
S268FGYLMsPREESPhosphoSitePlus

Dephosphorylation site
PTN5_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000379474G5RCOSMICMelanoma19074898
ENSP00000351342T432MCOSMICOvarian Cancer21720365
ENSP00000351342G5RCOSMICMelanoma19074898
ENSP00000379474E306KCOSMICMelanoma19074898
ENSP00000379474T432MCOSMICOvarian Cancer21720365
ENSP00000351342E306KCOSMICMelanoma19074898
ENSP00000379474K329ECOSMICOvarian Cancer21720365
ENSP00000351342P170ACOSMICMelanoma19074898
ENSP00000351342K329ECOSMICOvarian Cancer21720365

Differential expressed protein
PTN5_HUMAN is not differential expressed protein.

Hyperphosphorylation site
PTN5_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
PTN5_HUMANFYN_HUMANphosphatase -> substrateHPRD

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04010MAPK signaling pathway

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0001784phosphotyrosine bindingIDAmolecular_function
GO:0004725protein tyrosine phosphatase activityIEAmolecular_function
GO:0005789endoplasmic reticulum membraneIEAcellular_component
GO:0035335peptidyl-tyrosine dephosphorylationIEAbiological_process
GO:0006470protein dephosphorylationIEAbiological_process
GO:0016021integral to membraneTAScellular_component
GO:0016311dephosphorylationIEAbiological_process
GO:0006470protein dephosphorylationTASbiological_process
GO:0016791phosphatase activityIEAmolecular_function


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