Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:PTN3_HUMAN
Description:protein tyrosine phosphatase, non-receptor type 3 [Source:HGNC Symbol;Acc:9655]
Location:chr9 q31.3
Node attribute:phosphotase

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S359MRRSLsVEHLEPhosphoSitePlus; HPRD; phosphoELM; SysPTM
S367HLETKsLPSRSPhosphoSitePlus; HPRD; phosphoELM
S395KPRHSsADNLAHPRD; phosphoELM
S469APGSCsPDGVDPhosphoSitePlus
Y324NVLSQyWTMGSPhosphoSitePlus; HPRD
S394RKPRHsSADNLHPRD; phosphoELM
S835SLRVDsEPVLVY_phosphatasePhosphoSitePlus
Y244AGVAVyRKYICFERM_CPhosphoSitePlus
S835SLRVDsEPVLVphosphoELM
S372SLPSRsPPITPPhosphoSitePlus; HPRD; phosphoELM
S370TKSLPsRSPPIHPRD; phosphoELM
S459SSSSVsPSSNAPhosphoSitePlus
T376RSPPItPNWRSPhosphoSitePlus; HPRD; phosphoELM
S455LTQKSsSSVSPPhosphoSitePlus
S381TPNWRsPRLRHPhosphoSitePlus; HPRD; phosphoELM
S357PAMRRsLSVEHPhosphoSitePlus; HPRD; phosphoELM

Dephosphorylation site
PTN3_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000363667R385WCOSMICHead and Neck Cancer21798893
ENSP00000378308R371CCOSMICOvarian Cancer21720365
ENSP00000363667G768SCOSMICHead and Neck Cancer21984974
ENSP00000363667E193QCOSMICHead and Neck Cancer21798893
ENSP00000378308G768SCOSMICHead and Neck Cancer21984974
ENSP00000378308E193QCOSMICHead and Neck Cancer21798893
ENSP00000363667R371CCOSMICOvarian Cancer21720365
ENSP00000378308R385WCOSMICHead and Neck Cancer21798893
ENSP00000363667H812LCOSMICOvarian Cancer21720365
ENSP00000378308H812LCOSMICOvarian Cancer21720365
ENSP00000378308D811ECOSMICOvarian Cancer21720365
ENSP00000363667D811ECOSMICOvarian Cancer21720365
ENSP00000378308F578CCOSMICOvarian Cancer21720365
ENSP00000363667F578CCOSMICOvarian Cancer21720365

Differential expressed protein
PTN3_HUMAN is not differential expressed protein.

Hyperphosphorylation site
PTN3_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
PTN3_HUMANCD3Z_HUMANphosphatase -> substrateNetPath
PTN3_HUMANTERA_HUMANphosphatase -> substrateHPRD

Function Annotation
KEGG Pathway
PTN3_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0035335peptidyl-tyrosine dephosphorylationTASbiological_process
GO:0006470protein dephosphorylationIDAbiological_process
GO:0009898internal side of plasma membraneIDAcellular_component
GO:0004725protein tyrosine phosphatase activityIEAmolecular_function
GO:0001784phosphotyrosine bindingIPImolecular_function
GO:0008092cytoskeletal protein bindingIEAmolecular_function
GO:0005737cytoplasmIDAcellular_component
GO:0045930negative regulation of mitotic cell cycleIDAbiological_process
GO:0008138protein tyrosine/serine/threonine phosphatase actiIEAmolecular_function
GO:0016311dephosphorylationIEAbiological_process
GO:0016791phosphatase activityIEAmolecular_function
GO:0005856cytoskeletonIEAcellular_component
GO:0005515protein bindingIPImolecular_function
GO:0051045negative regulation of membrane protein ectodomainIMPbiological_process
GO:0051117ATPase bindingIPImolecular_function


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