Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:PTHY_HUMAN
Description:parathyroid hormone [Source:HGNC Symbol;Acc:9606]
Location:chr11 p15.2
Node attribute:ligand; gene

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S23CFLTKsDGKSVParathyroid; ABC_ATPasePhosphoSitePlus
S32SVKKRsVSEIQParathyroid; ABC_ATPasePhosphoSitePlus
S34KKRSVsEIQLMParathyroid; ABC_ATPasePhosphoSitePlus

Dephosphorylation site
PTHY_HUMAN do not have dephosphorylation site.

Mutation site
PTHY_HUMAN do not have mutation site.

Differential expressed protein
PTHY_HUMAN is not differential expressed protein.

Hyperphosphorylation site
PTHY_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
PTHY_HUMANPTH1R_HUMANligand -> receptorHPMR
PTHY_HUMANPTH2R_HUMANligand -> receptorHPMR
APEX1_HUMANPTHY_HUMANTF -> target geneTRANSFAC
CREB1_HUMANPTHY_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
PTHY_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0045944positive regulation of transcription from RNA polyIDAbiological_process
GO:0007266Rho protein signal transductionIEAbiological_process
GO:0051428peptide hormone receptor bindingIDAmolecular_function
GO:0030819positive regulation of cAMP biosynthetic processIDAbiological_process
GO:0005615extracellular spaceIEAcellular_component
GO:0046326positive regulation of glucose importIDAbiological_process
GO:0030501positive regulation of bone mineralizationIDAbiological_process
GO:0010468regulation of gene expressionIEAbiological_process
GO:0009967positive regulation of signal transductionIEAbiological_process
GO:0046058cAMP metabolic processTASbiological_process
GO:0007186G-protein coupled receptor signaling pathwayTASbiological_process
GO:0010468regulation of gene expressionIDAbiological_process
GO:0008628hormone-mediated apoptotic signaling pathwayTASbiological_process
GO:0000122negative regulation of transcription from RNA polyIDAbiological_process
GO:0007267cell-cell signalingTASbiological_process
GO:0001501skeletal system developmentTASbiological_process
GO:0003705RNA polymerase II distal enhancer sequence-specifiIMPmolecular_function
GO:0030819positive regulation of cAMP biosynthetic processIEAbiological_process
GO:0045725positive regulation of glycogen biosynthetic proceIDAbiological_process
GO:0045453bone resorptionNASbiological_process
GO:0045944positive regulation of transcription from RNA polyIEAbiological_process
GO:0034645cellular macromolecule biosynthetic processIDAbiological_process
GO:0007189adenylate cyclase-activating G-protein coupled recIEAbiological_process
GO:0006874cellular calcium ion homeostasisIEAbiological_process
GO:0005179hormone activityIEAmolecular_function
GO:0031856parathyroid hormone receptor bindingIEAmolecular_function
GO:0006874cellular calcium ion homeostasisNASbiological_process
GO:0005576extracellular regionNAScellular_component


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