| UniProt/SwissProt ID: | PTCRA_HUMAN |
| Description: | pre T-cell antigen receptor alpha [Source:HGNC Symbol;Acc:21290] |
| Location: | chr6 p21.1 |
| Node attribute: | gene |
| Phosphorylation site |
| PTCRA_HUMAN do not have phosphorylation site. |
| Dephosphorylation site |
| PTCRA_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000304447 | P54T | COSMIC | Ovarian Cancer | 21720365 | ENSP00000304447 | V52D | COSMIC | Ovarian Cancer | 21720365 | ENSP00000304447 | P54T | TCGA | Ovarian Cancer | 21720365, 18772890 | ENSP00000304447 | V52D | TCGA | Ovarian Cancer | 21720365, 18772890 |
| Differential expressed protein |
| PTCRA_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| PTCRA_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| GLI1_HUMAN | PTCRA_HUMAN | TF -> target gene | KEGG |
| RBPJL_HUMAN | PTCRA_HUMAN | TF -> target gene | KEGG |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa05202 | Transcriptional misregulation in cancer |
| hsa04330 | Notch signaling pathway |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0070244 | negative regulation of thymocyte apoptotic process | IEA | biological_process |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0016021 | integral to membrane | IEA | cellular_component |