Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:PRG2_HUMAN
Description:proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) [Source:HGNC Symbol;Acc:9362]
Location:chr11 q12.1
Node attribute:substrate

Phosphorylation site
PRG2_HUMAN do not have phosphorylation site.

Dephosphorylation site
PRG2_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000433016R179CBIOMARTColorectal Cancer21930507, 21930502
ENSP00000312134R179CSjoblom2006, COSMICIntestines Cancer16959974
ENSP00000312134R179CHPIColorectal Cancer16959974

Differential expressed protein
PRG2_HUMAN is not differential expressed protein.

Hyperphosphorylation site
PRG2_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
UHMK1_HUMANPRG2_HUMANkinase -> substrateRegPhos; Robert H Newman (2013)
MK01_HUMANPRG2_HUMANkinase -> substrateHPRD; Robert H Newman (2013)
MK03_HUMANPRG2_HUMANkinase -> substrateRobert H Newman (2013)
KPCA_HUMANPRG2_HUMANkinase -> substrateHPRD
ZAGL2_HUMANPRG2_HUMANkinase -> substrateRegPhos

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa05310Asthma

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0006955immune responseIEAbiological_process
GO:0005576extracellular regionIEAcellular_component
GO:0008201heparin bindingIEAmolecular_function
GO:0030133transport vesicleIEAcellular_component
GO:0042742defense response to bacteriumIEAbiological_process
GO:0030246carbohydrate bindingIEAmolecular_function


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