| UniProt/SwissProt ID: | PPR17_HUMAN |
| Description: | protein phosphatase 1, regulatory subunit 17 [Source:HGNC Symbol;Acc:16973] |
| Location: | chr7 p14.3 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T119 | PRRKDtPALHM | PRKACA | HPRD |
| S25 | LDPRCsHLDDL | DUF2602 | PhosphoSitePlus |
| T68 | PRRKDtPALHI | PRKACA | HPRD |
| T68 | PRRKDtPALHI | PhosphoSitePlus | |
| T119 | PRRKDtPALHM | PRKG1 | HPRD |
| T68 | PRRKDtPALHI | PRKG1 | HPRD |
| T119 | PRRKDtPALHM | PhosphoSitePlus | |
| Dephosphorylation site |
| PPR17_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000340125 | K43N | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000340125 | D136G | COSMIC | Ovarian Cancer | 21720365 | ENSP00000340125 | V50I | COSMIC | Central Nervous System Neoplasms | 18772396 |
| Differential expressed protein |
| PPR17_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| PPR17_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| KGP1_HUMAN | PPR17_HUMAN | kinase -> substrate | HPRD |
| KPCA_HUMAN | PPR17_HUMAN | kinase -> substrate | HPRD |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04730 | Long-term depression |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0010921 | regulation of phosphatase activity | ISS | biological_process |
| GO:0007243 | intracellular protein kinase cascade | TAS | biological_process |
| GO:0007610 | behavior | TAS | biological_process |
| GO:0004864 | protein phosphatase inhibitor activity | TAS | molecular_function |
| GO:0006468 | protein phosphorylation | TAS | biological_process |
| GO:0019212 | phosphatase inhibitor activity | IEA | molecular_function |
| GO:0005575 | cellular_component | ND | cellular_component |
| GO:0004864 | protein phosphatase inhibitor activity | IEA | molecular_function |
| GO:0010921 | regulation of phosphatase activity | IEA | biological_process |
| GO:0007165 | signal transduction | TAS | biological_process |
| GO:0004865 | protein serine/threonine phosphatase inhibitor act | IEA | molecular_function |
| GO:0007417 | central nervous system development | TAS | biological_process |