| UniProt/SwissProt ID: | PP4C_HUMAN |
| Description: | protein phosphatase 4, catalytic subunit [Source:HGNC Symbol;Acc:9319] |
| Location: | chr16 p11.2 |
| Node attribute: | phosphotase |
| Phosphorylation site |
| PP4C_HUMAN do not have phosphorylation site. |
| Dephosphorylation site |
| PP4C_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000455995 | P169S | COSMIC | Melanoma | ENSP00000279387 | P169S | COSMIC | Melanoma |
| Differential expressed protein |
| PP4C_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| PP4C_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| PP4C_HUMAN | IRS4_HUMAN | phosphatase -> substrate | NetPath |
| Function Annotation |
| KEGG Pathway |
| PP4C_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0004722 | protein serine/threonine phosphatase activity | IDA | molecular_function |
| GO:0004704 | NF-kappaB-inducing kinase activity | NAS | molecular_function |
| GO:0005737 | cytoplasm | IDA | cellular_component |
| GO:0000226 | microtubule cytoskeleton organization | NAS | biological_process |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0016787 | hydrolase activity | IEA | molecular_function |
| GO:0046872 | metal ion binding | NAS | molecular_function |
| GO:0010569 | regulation of double-strand break repair via homol | IMP | biological_process |
| GO:0038061 | NIK/NF-kappaB cascade | NAS | biological_process |
| GO:0005737 | cytoplasm | IEA | cellular_component |
| GO:0030289 | protein phosphatase 4 complex | IEA | cellular_component |
| GO:0005634 | nucleus | NAS | cellular_component |
| GO:0005886 | plasma membrane | IDA | cellular_component |
| GO:0005813 | centrosome | NAS | cellular_component |