Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:POGZ_HUMAN
Description:pogo transposable element with ZNF domain [Source:HGNC Symbol;Acc:18801]
Location:chr1 q21.3
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S274QLAVQsPGQSNPhosphoSitePlus; HPRD; phosphoELM
S1360EQLKLsGEHSEPhosphoSitePlus; HPRD
S651TVPVSsNDTPPHPRD
S440PKVATsFRCPHHPRD
S392PIPALsPPTKVHPRD
S1259PAGCSsKIQPLHPRD
S198SQQTKsTPSTSHPRD
S493PKVATsFRCPHPhosphoSitePlus; HPRD
S1313GEHSEsSTPRPHPRD
T205PSTSTtPTATQHPRD
S437VASTPsSTPIPPhosphoSitePlus
T654VSSNDtPPSALHPRD
T1368HSESStPRPRSPhosphoSitePlus; HPRD; phosphoELM
T229QSNQTtNPKLAHPRD
T435APVAStPSSTPPhosphoSitePlus
S1364LSGEHsESSTPPhosphoSitePlus; HPRD; phosphoELM; SysPTM
S425AAKPPsPEKTAPhosphoSitePlus; HPRD; phosphoELM; SysPTM
S221QLAVQsPGQSNHPRD
S746AVRKMsVMGRQPhosphoSitePlus
T448ALSPPtKVPEPPhosphoSitePlus; HPRD
S1366GEHSEsSTPRPPhosphoSitePlus; HPRD; phosphoELM
T439STPSStPIPALPhosphoSitePlus
Y33SVVEDyNSVDKPhosphoSitePlus
S251SQQTKsTPSTSHPRD
T686GLKPGtKVTIRPhosphoSitePlus
S1338DGNINsPTRNAPhosphoSitePlus; HPRD; phosphoELM; SysPTM
S416LDSEPsVPSAAHPRD; phosphoELM
S292APSFPsPPAVSPhosphoSitePlus
T1340NINSPtRNADMPhosphoSitePlus
S949DQDEGsPVTQEPhosphoSitePlus
T780LCRYStCCSRAPhosphoSitePlus
T707VSSNDtPPSALPhosphoSitePlus; HPRD; phosphoELM
S1206PAGCSsKIQPLHPRD
S1352EELIAsLEEQLPhosphoSitePlus
T429PSPEKtAPVASPhosphoSitePlus; HPRD; phosphoELM
T492FPKVAtSFRCPPhosphoSitePlus; HPRD
S1236HRTHLsEEVLAHPRD
S1169TACQRsKGMLVHPRD
T1315HSESStPRPRSHPRD
S419EPSVPsAAKPPPhosphoSitePlus; HPRD; phosphoELM; SysPTM
S1311LSGEHsESSTPHPRD
S333PSLGQsPGPVVPhosphoSitePlus; HPRD; phosphoELM; SysPTM
S704TVPVSsNDTPPPhosphoSitePlus; HPRD
S434TAPVAsTPSSTPhosphoSitePlus
T689PGTKVtIRASRPhosphoSitePlus
S445PIPALsPPTKVPhosphoSitePlus; HPRD; phosphoELM
T258PSTSTtPTATQPhosphoSitePlus; HPRD
S363LDSEPsVPSAAHPRD
S1367EHSESsTPRPRPhosphoSitePlus; phosphoELM
T395ALSPPtKVPEPHPRD
S1222TACQRsKGMLVHPRD
S1183HRTHLsEEVLAHPRD
S366EPSVPsAAKPPHPRD
S280PSLGQsPGPVVHPRD
S1013RRFQAsQGENLHTH_28PhosphoSitePlus
T439FPKVAtSFRCPHPRD
S1285DGNINsPTRNAHPRD
S1307EQLKLsGEHSEHPRD
S372AAKPPsPEKTAHPRD
T282QSNQTtNPKLAHPRD
T376PSPEKtAPVASHPRD

Dephosphorylation site
POGZ_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000357856D317HBIOMARTBreast Cancer21930507, 21930502
ENSP00000271715G192DCOSMICOvarian Cancer21720365
ENSP00000418408D359HBIOMARTBreast Cancer21930507, 21930502
ENSP00000376484D359HBIOMARTBreast Cancer21930507, 21930502
ENSP00000354467D359HBIOMARTBreast Cancer21930507, 21930502
ENSP00000271715A568SBIOMARTBreast Cancer21930507, 21930502
ENSP00000271715D412HBIOMARTBreast Cancer21930507, 21930502
ENSP00000418408A515SBIOMARTBreast Cancer21930507, 21930502
ENSP00000357856A473SBIOMARTBreast Cancer21930507, 21930502
ENSP00000376484A515SBIOMARTBreast Cancer21930507, 21930502
ENSP00000271715G1167CCOSMICOvarian Cancer21720365
ENSP00000271715L235VCOSMICOvarian Cancer21720365
ENSP00000354467A515SBIOMARTBreast Cancer21930507, 21930502
ENSP00000271715R1087*COSMICSkin Cancer21984974

Differential expressed protein
POGZ_HUMAN is not differential expressed protein.

Hyperphosphorylation site
POGZ_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
NEK4_HUMANPOGZ_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
POGZ_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0008270zinc ion bindingIEAmolecular_function
GO:0051382kinetochore assemblyIMPbiological_process
GO:0005622intracellularIEAcellular_component
GO:0051301cell divisionIEAbiological_process
GO:0003677DNA bindingIEAmolecular_function
GO:0005737cytoplasmIDAcellular_component
GO:0005515protein bindingIPImolecular_function
GO:0000790nuclear chromatinIDAcellular_component
GO:0003676nucleic acid bindingIEAmolecular_function
GO:0005634nucleusIDAcellular_component
GO:0007064mitotic sister chromatid cohesionIMPbiological_process


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