| UniProt/SwissProt ID: | PMYT1_HUMAN |
| Description: | protein kinase, membrane associated tyrosine/threonine 1 [Source:HGNC Symbol;Acc:29650] |
| Location: | chr16 p13.3 |
| Node attribute: | kinase; substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S469 | DALDLsDINSE | PhosphoSitePlus; HPRD; phosphoELM; SysPTM | |
| S120 | RLGHGsYGEVF | HPRD; phosphoELM; SysPTM | |
| S48 | RPRGLsRSLPP | PhosphoSitePlus; HPRD | |
| S454 | TVGSTsTPRSR | PhosphoSitePlus; HPRD | |
| S50 | RGLSRsLPPPP | PhosphoSitePlus; HPRD; phosphoELM | |
| S141 | YAVKRsMSPFR | HPRD | |
| S426 | LLLDSsLSSNW | PhosphoSitePlus | |
| S473 | LSDINsEPPRG | PhosphoSitePlus; HPRD; phosphoELM | |
| S160 | LAEVGsHEKVG | HPRD; SysPTM | |
| S416 | ATPPGsPPCSL | PhosphoSitePlus | |
| T461 | PRSRCtPRDAL | PhosphoSitePlus | |
| S120 | RLGHGsYGEVF | Pkinase | PhosphoSitePlus; SysPTM |
| T412 | LGPPAtPPGSP | PhosphoSitePlus | |
| T495 | SLFEDtLD | PLK1 | HPRD; phosphoELM; SysPTM |
| S94 | SETLQsPGYDP | PhosphoSitePlus; HPRD; phosphoELM; RegPhos; SysPTM | |
| S458 | TSTPRsRCTPR | PhosphoSitePlus | |
| S40 | AEPGFsLKRPR | PhosphoSitePlus; HPRD; phosphoELM | |
| T24 | PPLSGtPIPVP | HPRD; phosphoELM | |
| S479 | EPPRGsFPSFE | PhosphoSitePlus; HPRD | |
| Y136 | EDGRLyAVKRS | Pkinase | PhosphoSitePlus |
| S441 | LGPSLsPEAVL | PhosphoSitePlus | |
| S141 | YAVKRsMSPFR | Pkinase | PhosphoSitePlus |
| T455 | VGSTStPRSRC | PhosphoSitePlus | |
| T495 | SLFEDtLDPT_ | PhosphoSitePlus; SysPTM | |
| S426 | LLLDSsLSSNW | PLK1 | HPRD; phosphoELM; RegPhos |
| S22 | TPPPLsGTPIP | HPRD | |
| S60 | PPAKGsIPISR | HPRD | |
| T495 | SLFEDtLDPT | PLK1 | RegPhos; SysPTM |
| T71 | LFPPRtPGWHQ | PhosphoSitePlus | |
| S160 | LAEVGsHEKVG | Pkinase | PhosphoSitePlus; SysPTM |
| T17 | MPTEGtPPPLS | PhosphoSitePlus; HPRD; phosphoELM; SysPTM | |
| Y97 | LQSPGyDPSRP | HPRD; phosphoELM | |
| S143 | VKRSMsPFRGP | Pkinase | PhosphoSitePlus; SysPTM |
| S143 | VKRSMsPFRGP | HPRD; phosphoELM; RegPhos; SysPTM | |
| Dephosphorylation site |
| PMYT1_HUMAN do not have dephosphorylation site. |
| Mutation site |
| PMYT1_HUMAN do not have mutation site. |
| Differential expressed protein |
| PMYT1_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| PMYT1_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| ZAGL2_HUMAN | PMYT1_HUMAN | kinase -> substrate | RegPhos |
| PMYT1_HUMAN | CDK1_HUMAN | kinase -> substrate | RegPhos |
| PLK1_HUMAN | PMYT1_HUMAN | kinase -> substrate | RegPhos; Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04914 | Progesterone-mediated oocyte maturation |
| hsa04114 | Oocyte meiosis |
| hsa04110 | Cell cycle |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0051726 | regulation of cell cycle | TAS | biological_process |
| GO:0005737 | cytoplasm | IEA | cellular_component |
| GO:0004672 | protein kinase activity | IEA | molecular_function |
| GO:0007088 | regulation of mitosis | TAS | biological_process |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0046872 | metal ion binding | IEA | molecular_function |
| GO:0005783 | endoplasmic reticulum | TAS | cellular_component |
| GO:0004713 | protein tyrosine kinase activity | IEA | molecular_function |
| GO:0007049 | cell cycle | IEA | biological_process |
| GO:0005634 | nucleus | IEA | cellular_component |
| GO:0004674 | protein serine/threonine kinase activity | IEA | molecular_function |
| GO:0000086 | G2/M transition of mitotic cell cycle | TAS | biological_process |
| GO:0005789 | endoplasmic reticulum membrane | IEA | cellular_component |
| GO:0005654 | nucleoplasm | TAS | cellular_component |
| GO:0010923 | negative regulation of phosphatase activity | IDA | biological_process |
| GO:0000079 | regulation of cyclin-dependent protein kinase acti | TAS | biological_process |
| GO:0000082 | G1/S transition of mitotic cell cycle | TAS | biological_process |
| GO:0005794 | Golgi apparatus | TAS | cellular_component |
| GO:0016301 | kinase activity | IDA | molecular_function |
| GO:0016020 | membrane | IEA | cellular_component |
| GO:0000278 | mitotic cell cycle | TAS | biological_process |
| GO:0016772 | transferase activity, transferring phosphorus-cont | IEA | molecular_function |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0000139 | Golgi membrane | IEA | cellular_component |
| GO:0006468 | protein phosphorylation | IEA | biological_process |
| GO:0007067 | mitosis | TAS | biological_process |