Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:PMYT1_HUMAN
Description:protein kinase, membrane associated tyrosine/threonine 1 [Source:HGNC Symbol;Acc:29650]
Location:chr16 p13.3
Node attribute:kinase; substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S469DALDLsDINSEPhosphoSitePlus; HPRD; phosphoELM; SysPTM
S120RLGHGsYGEVFHPRD; phosphoELM; SysPTM
S48RPRGLsRSLPPPhosphoSitePlus; HPRD
S454TVGSTsTPRSRPhosphoSitePlus; HPRD
S50RGLSRsLPPPPPhosphoSitePlus; HPRD; phosphoELM
S141YAVKRsMSPFRHPRD
S426LLLDSsLSSNWPhosphoSitePlus
S473LSDINsEPPRGPhosphoSitePlus; HPRD; phosphoELM
S160LAEVGsHEKVGHPRD; SysPTM
S416ATPPGsPPCSLPhosphoSitePlus
T461PRSRCtPRDALPhosphoSitePlus
S120RLGHGsYGEVFPkinasePhosphoSitePlus; SysPTM
T412LGPPAtPPGSPPhosphoSitePlus
T495SLFEDtLDPLK1HPRD; phosphoELM; SysPTM
S94SETLQsPGYDPPhosphoSitePlus; HPRD; phosphoELM; RegPhos; SysPTM
S458TSTPRsRCTPRPhosphoSitePlus
S40AEPGFsLKRPRPhosphoSitePlus; HPRD; phosphoELM
T24PPLSGtPIPVPHPRD; phosphoELM
S479EPPRGsFPSFEPhosphoSitePlus; HPRD
Y136EDGRLyAVKRSPkinasePhosphoSitePlus
S441LGPSLsPEAVLPhosphoSitePlus
S141YAVKRsMSPFRPkinasePhosphoSitePlus
T455VGSTStPRSRCPhosphoSitePlus
T495SLFEDtLDPT_PhosphoSitePlus; SysPTM
S426LLLDSsLSSNWPLK1HPRD; phosphoELM; RegPhos
S22TPPPLsGTPIPHPRD
S60PPAKGsIPISRHPRD
T495SLFEDtLDPTPLK1RegPhos; SysPTM
T71LFPPRtPGWHQPhosphoSitePlus
S160LAEVGsHEKVGPkinasePhosphoSitePlus; SysPTM
T17MPTEGtPPPLSPhosphoSitePlus; HPRD; phosphoELM; SysPTM
Y97LQSPGyDPSRPHPRD; phosphoELM
S143VKRSMsPFRGPPkinasePhosphoSitePlus; SysPTM
S143VKRSMsPFRGPHPRD; phosphoELM; RegPhos; SysPTM

Dephosphorylation site
PMYT1_HUMAN do not have dephosphorylation site.

Mutation site
PMYT1_HUMAN do not have mutation site.

Differential expressed protein
PMYT1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
PMYT1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
ZAGL2_HUMANPMYT1_HUMANkinase -> substrateRegPhos
PMYT1_HUMANCDK1_HUMANkinase -> substrateRegPhos
PLK1_HUMANPMYT1_HUMANkinase -> substrateRegPhos; Robert H Newman (2013)

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04914Progesterone-mediated oocyte maturation
hsa04114Oocyte meiosis
hsa04110Cell cycle

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0051726regulation of cell cycleTASbiological_process
GO:0005737cytoplasmIEAcellular_component
GO:0004672protein kinase activityIEAmolecular_function
GO:0007088regulation of mitosisTASbiological_process
GO:0005524ATP bindingIEAmolecular_function
GO:0046872metal ion bindingIEAmolecular_function
GO:0005783endoplasmic reticulumTAScellular_component
GO:0004713protein tyrosine kinase activityIEAmolecular_function
GO:0007049cell cycleIEAbiological_process
GO:0005634nucleusIEAcellular_component
GO:0004674protein serine/threonine kinase activityIEAmolecular_function
GO:0000086G2/M transition of mitotic cell cycleTASbiological_process
GO:0005789endoplasmic reticulum membraneIEAcellular_component
GO:0005654nucleoplasmTAScellular_component
GO:0010923negative regulation of phosphatase activityIDAbiological_process
GO:0000079regulation of cyclin-dependent protein kinase actiTASbiological_process
GO:0000082G1/S transition of mitotic cell cycleTASbiological_process
GO:0005794Golgi apparatusTAScellular_component
GO:0016301kinase activityIDAmolecular_function
GO:0016020membraneIEAcellular_component
GO:0000278mitotic cell cycleTASbiological_process
GO:0016772transferase activity, transferring phosphorus-contIEAmolecular_function
GO:0005515protein bindingIPImolecular_function
GO:0000139Golgi membraneIEAcellular_component
GO:0006468protein phosphorylationIEAbiological_process
GO:0007067mitosisTASbiological_process


Fatal error: Uncaught Error: Call to undefined function mysql_close() in /usr/local/apache/htdocs/PhoSigNet/include/locateconfig.inc.php:23 Stack trace: #0 /usr/local/apache/htdocs/PhoSigNet/proteintable.php(435): db_disconnect(Object(mysqli)) #1 {main} thrown in /usr/local/apache/htdocs/PhoSigNet/include/locateconfig.inc.php on line 23