Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:PLXD1_HUMAN
Description:plexin D1 [Source:HGNC Symbol;Acc:9107]
Location:chr3 q22.1
Node attribute:receptor

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S1075VITAIsPRRSPTIGPhosphoSitePlus
T1661DKKDNtLGRVKPlexin_cytoplPhosphoSitePlus
S838ARFLDsPEPMTPhosphoSitePlus
S1693KSHRQsHRKKVPlexin_cytoplPhosphoSitePlus
Y1367KCSSLyEERYVPlexin_cytoplPhosphoSitePlus
S1079ISPRRsPVSGGTIGPhosphoSitePlus
T1534SIDAItGKARYHPRD
Y1673LDTEKyFHLVLPlexin_cytoplPhosphoSitePlus
T1088GGRTItVAGERTIGPhosphoSitePlus
S1649IPEGAsLAMSLPlexin_cytoplPhosphoSitePlus
Y1642NTLAHyKIPEGPlexin_cytoplPhosphoSitePlus
T1086VSGGRtITVAGTIGPhosphoSitePlus
T1661DKKDNtLGRVKHPRD

Dephosphorylation site
PLXD1_HUMAN do not have dephosphorylation site.

Mutation site
PLXD1_HUMAN do not have mutation site.

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000317128Testicular CancerNormal vs. Cancercell lineDown18489135

Hyperphosphorylation site
PLXD1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
SEM3E_HUMANPLXD1_HUMANligand -> receptorHPMR

Function Annotation
KEGG Pathway
PLXD1_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0045765regulation of angiogenesisISSbiological_process
GO:0007416synapse assemblyIEAbiological_process
GO:0005886plasma membraneTAScellular_component
GO:0071526semaphorin-plexin signaling pathwayISSbiological_process
GO:0005887integral to plasma membraneIEAcellular_component
GO:0005515protein bindingIEAmolecular_function
GO:0001525angiogenesisISSbiological_process
GO:0004872receptor activityIEAmolecular_function
GO:0043542endothelial cell migrationISSbiological_process
GO:0007165signal transductionIEAbiological_process
GO:0001569patterning of blood vesselsIEAbiological_process
GO:0045765regulation of angiogenesisIEAbiological_process
GO:0007411axon guidanceTASbiological_process
GO:0071526semaphorin-plexin signaling pathwayIEAbiological_process
GO:0030334regulation of cell migrationIEAbiological_process
GO:0005887integral to plasma membraneISScellular_component
GO:0060666dichotomous subdivision of terminal units involvedIEAbiological_process
GO:0043542endothelial cell migrationIEAbiological_process
GO:0030334regulation of cell migrationISSbiological_process
GO:0007275multicellular organismal developmentIEAbiological_process
GO:0017154semaphorin receptor activityISSmolecular_function
GO:0001525angiogenesisIEAbiological_process
GO:0016020membraneIEAcellular_component
GO:0017154semaphorin receptor activityIEAmolecular_function
GO:0005622intracellularIEAcellular_component
GO:0007416synapse assemblyISSbiological_process


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