Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:PLXB2_HUMAN
Description:plexin B2 [Source:HGNC Symbol;Acc:9104]
Location:chr22 q13.33
Node attribute:receptor

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y1748KEISTyKKMVEPlexin_cytoplPhosphoSitePlus
Y1621AITEIyLTRLLPlexin_cytopl; RasGAPPhosphoSitePlus
Y1422AGEPLyKLFKAPlexin_cytopl; RasGAPPhosphoSitePlus
Y1412ICLYQyLKDSAPlexin_cytopl; RasGAPPhosphoSitePlus
Y1410MSICLyQYLKDPlexin_cytopl; RasGAPPhosphoSitePlus
S1570QQPEDsQQDLPPlexin_cytopl; RasGAPPhosphoSitePlus
T1614KEKERtKAITEPlexin_cytopl; RasGAPPhosphoSitePlus
S1224CYWRKsQQAERRAMPPhosphoSitePlus
S1627LTRLLsVKGTLPlexin_cytopl; RasGAPPhosphoSitePlus
Y1741SNKLLyAKEISPlexin_cytoplPhosphoSitePlus
Y1499IIDQVyRGQPCPlexin_cytopl; RasGAPPhosphoSitePlus
Y1349ARAKVyFASLLPlexin_cytoplPhosphoSitePlus
S1325SNLLNsKSFLIPlexin_cytoplPhosphoSitePlus
T1124LNKAMtLQEAEPhosphoSitePlus; HPRD
Y419RILKVyLTPDGSemaPhosphoSitePlus
S1327LLNSKsFLINFPlexin_cytoplPhosphoSitePlus
Y1231QAEREyEKIKSPhosphoSitePlus
S452SGDLGsLYAMTPhosphoSitePlus; HPRD
S1320ALYQFsNLLNSPlexin_cytoplPhosphoSitePlus
T1623TEIYLtRLLSVPlexin_cytopl; RasGAPPhosphoSitePlus

Dephosphorylation site
PLXB2_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000352288R659PBIOMARTNeoplasms by Histologic Type21930507, 21930502

Differential expressed protein
PLXB2_HUMAN is not differential expressed protein.

Hyperphosphorylation site
PLXB2_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
SEM4D_HUMANPLXB2_HUMANligand -> receptorHPMR

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04360Axon guidance

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0016020membraneIEAcellular_component
GO:0007275multicellular organismal developmentIEAbiological_process
GO:0071526semaphorin-plexin signaling pathwayIEAbiological_process
GO:0001932regulation of protein phosphorylationIEAbiological_process
GO:0071526semaphorin-plexin signaling pathwayISSbiological_process
GO:0008360regulation of cell shapeIEAbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0005622intracellularIEAcellular_component
GO:0050772positive regulation of axonogenesisIEAbiological_process
GO:0005887integral to plasma membraneIEAcellular_component
GO:0007405neuroblast proliferationIEAbiological_process
GO:0007165signal transductionIEAbiological_process
GO:0001843neural tube closureIEAbiological_process
GO:0032319regulation of Rho GTPase activityIEAbiological_process
GO:0007420brain developmentIEAbiological_process
GO:0005096GTPase activator activityIEAmolecular_function
GO:0005515protein bindingIEAmolecular_function
GO:0017154semaphorin receptor activityIEAmolecular_function
GO:0004872receptor activityIEAmolecular_function
GO:2001222regulation of neuron migrationIEAbiological_process


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