Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:PLCZ1_HUMAN
Description:phospholipase C, zeta 1 [Source:HGNC Symbol;Acc:19218]
Location:chr12 p12.3
Node attribute:PPI(source)

Phosphorylation site
PLCZ1_HUMAN do not have phosphorylation site.

Dephosphorylation site
PLCZ1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000266505E538QCOSMICHead and Neck Cancer21798893
ENSP00000266505R584CCOSMICLung Cancer
ENSP00000266505G592CCOSMICOvarian Cancer21720365
ENSP00000266505D12NCOSMICSkin Cancer21984974
ENSP00000266505G206RCOSMICMelanoma21499247

Differential expressed protein
PLCZ1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
PLCZ1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
PLCZ1_HUMANITPR1_HUMANotherKEGG
PLCZ1_HUMANKPCA_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa01100Metabolic pathways
hsa04070Phosphatidylinositol signaling system
hsa04020Calcium signaling pathway
hsa04114Oocyte meiosis
hsa00562Inositol phosphate metabolism

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0048471perinuclear region of cytoplasmIEAcellular_component
GO:0008081phosphoric diester hydrolase activityIEAmolecular_function
GO:0005634nucleusIEAcellular_component
GO:0007275multicellular organismal developmentIEAbiological_process
GO:0004629phospholipase C activityIEAmolecular_function
GO:0004435phosphatidylinositol phospholipase C activityIEAmolecular_function
GO:0004871signal transducer activityIEAmolecular_function
GO:0006629lipid metabolic processIEAbiological_process
GO:0016042lipid catabolic processIEAbiological_process
GO:0005509calcium ion bindingIEAmolecular_function
GO:0007343egg activationIEAbiological_process
GO:0007165signal transductionIEAbiological_process
GO:0035556intracellular signal transductionIEAbiological_process
GO:0006816calcium ion transportIEAbiological_process
GO:0005515protein bindingIEAmolecular_function


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