Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:PKN3_HUMAN
Description:protein kinase N3 [Source:HGNC Symbol;Acc:17999]
Location:chr9 q34.11
Node attribute:kinase; substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T508LGEEMtPPPKPPhosphoSitePlus; HPRD; SysPTM
T722STFCGtPEFLAHPRD; phosphoELM; SysPTM
T716GFGDRtSTFCGHPRD
T718GDRTStFCGTPPkinase_AGCPhosphoSitePlus
T860LPPALtPPAPHHPRD; phosphoELM; SysPTM
S544TRRGPsPPASPPKN3HPRD; SysPTM
T820QPFFRtTNWQAPhosphoSitePlus
T492ASDPAtPSNFLPhosphoSitePlus
T718GDRTStFCGTPHPRD; phosphoELM
T527PTSEEtPRTKRPhosphoSitePlus
T550PPASPtRKPPRPhosphoSitePlus; phosphoELM
S544TRRGPsPPASPPhosphoSitePlus; phosphoELM; SysPTM
T860LPPALtPPAPHPkinase_CPhosphoSitePlus; SysPTM
T722STFCGtPEFLAPkinase_AGCPhosphoSitePlus; SysPTM
S717FGDRTsTFCGTPkinase_AGCPhosphoSitePlus
S307AALASsPSEGWPhosphoSitePlus; HPRD; SysPTM
S309LASSPsEGWLRHPRD; phosphoELM
T550PPASPtRKPPRPKN3HPRD
T523LPQEPtSEETPHPRD
S548PSPPAsPTRKPPhosphoSitePlus; HPRD; phosphoELM
T716GFGDRtSTFCGPkinase_AGCPhosphoSitePlus
S299AVPGRsPAAALPhosphoSitePlus

Dephosphorylation site
PKN3_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000291906G713RDing2008, BIOMARTLung Cancer18948947, 21930507, 21930502
ENSP00000291906S307IDing2008, BIOMARTLung Cancer18948947, 21930507, 21930502

Differential expressed protein
PKN3_HUMAN is not differential expressed protein.

Hyperphosphorylation site
PKN3_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
PKN3_HUMANBPL1_HUMANkinase -> substrateRobert H Newman (2013)
PKN3_HUMANPKN3_HUMANkinase -> substrateHPRD

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa05132Salmonella infection

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0004713protein tyrosine kinase activityIEAmolecular_function
GO:0005515protein bindingIPImolecular_function
GO:0005794Golgi apparatusTAScellular_component
GO:0005634nucleusIEAcellular_component
GO:0004697protein kinase C activityIEAmolecular_function
GO:0010631epithelial cell migrationIDAbiological_process
GO:0004672protein kinase activityTASmolecular_function
GO:0016772transferase activity, transferring phosphorus-contIEAmolecular_function
GO:0006468protein phosphorylationTASbiological_process
GO:0048471perinuclear region of cytoplasmIEAcellular_component
GO:0005622intracellularIEAcellular_component
GO:0007165signal transductionIEAbiological_process
GO:0005524ATP bindingIEAmolecular_function
GO:0004674protein serine/threonine kinase activityIEAmolecular_function


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