| UniProt/SwissProt ID: | PHOS_HUMAN |
| Description: | phosducin [Source:HGNC Symbol;Acc:8759] |
| Location: | chr1 q31.1 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S54 | ILRQMsSPQSR | CaMK2a | RegPhos |
| S73 | VSRKMsIQEYE | PRKACA | HPRD |
| S73 | VSRKMsIQEYE | PKACa | RegPhos |
| S73 | VSRKMsIQEYE | PKA_group | RegPhos |
| S21 | VSRKMsIQEYE | CAMK2A | HPRD |
| S73 | VSRKMsIQEYE | CAMK2A | HPRD |
| S54 | ILRQMsSPQSR | CAMK2A | HPRD |
| S2 | PQSR | CAMK2A | HPRD |
| S21 | VSRKMsIQEYE | PRKACA | HPRD |
| S73 | VSRKMsIQEYE | CaMK2a | RegPhos |
| S36 | KFKLEsQDSDS | Phosducin | PhosphoSitePlus |
| Dephosphorylation site |
| PHOS_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000375855 | E48K | COSMIC | Melanoma | 21499247 |
| Differential expressed protein |
| PHOS_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| PHOS_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| KPCZ_HUMAN | PHOS_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| KCC2A_HUMAN | PHOS_HUMAN | kinase -> substrate | HPRD |
| KPCA_HUMAN | PHOS_HUMAN | kinase -> substrate | HPRD |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04740 | Olfactory transduction |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005829 | cytosol | IEA | cellular_component |
| GO:0005634 | nucleus | IDA | cellular_component |
| GO:0001917 | photoreceptor inner segment | IEA | cellular_component |
| GO:0005737 | cytoplasm | IDA | cellular_component |
| GO:0007601 | visual perception | IEA | biological_process |
| GO:0015629 | actin cytoskeleton | IDA | cellular_component |
| GO:0007186 | G-protein coupled receptor signaling pathway | TAS | biological_process |
| GO:0007602 | phototransduction | TAS | biological_process |
| GO:0001750 | photoreceptor outer segment | IEA | cellular_component |
| GO:0004859 | phospholipase inhibitor activity | TAS | molecular_function |