| UniProt/SwissProt ID: | PHKG1_HUMAN |
| Description: | phosphorylase kinase, gamma 1 (muscle) [Source:HGNC Symbol;Acc:8930] |
| Location: | chr7 p11.2 |
| Node attribute: | kinase; substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S31 | LGRGVsSVVRR | PHKg1 | RegPhos |
| S31 | LGRGVsSVVRR | PHKG1 | HPRD |
| S32 | GRGVSsVVRRC | Pkinase_CAMK | PhosphoSitePlus |
| S31 | LGRGVsSVVRR | PHK_group | phosphoELM; RegPhos |
| S82 | ILRKVsGHPNI | PHKg1 | RegPhos |
| Y350 | RLIDAyAFRIY | PhosphoSitePlus | |
| S82 | ILRKVsGHPNI | PHKG1 | HPRD |
| S31 | LGRGVsSVVRR | Pkinase_CAMK | PhosphoSitePlus |
| S82 | ILRKVsGHPNI | PHK_group | phosphoELM; RegPhos |
| Y338 | VIRDPyALRPL | PhosphoSitePlus | |
| Dephosphorylation site |
| PHKG1_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000297373 | V48M | Greenman2007 | Intestines Cancer | 17344846, 18428421 | ENSP00000297373 | V48M | HPI | Colorectal Cancer | 17344846 |
| Differential expressed protein |
| PHKG1_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| PHKG1_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| PHKG1_HUMAN | TAU_HUMAN | kinase -> substrate | HPRD |
| PHKG1_HUMAN | PHKG1_HUMAN | kinase -> substrate | HPRD |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04020 | Calcium signaling pathway |
| hsa04910 | Insulin signaling pathway |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0006468 | protein phosphorylation | IEA | biological_process |
| GO:0044281 | small molecule metabolic process | TAS | biological_process |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0004672 | protein kinase activity | IEA | molecular_function |
| GO:0005829 | cytosol | TAS | cellular_component |
| GO:0005964 | phosphorylase kinase complex | IEA | cellular_component |
| GO:0050321 | tau-protein kinase activity | IEA | molecular_function |
| GO:0004713 | protein tyrosine kinase activity | IEA | molecular_function |
| GO:0016020 | membrane | IEA | cellular_component |
| GO:0005977 | glycogen metabolic process | IEA | biological_process |
| GO:0004689 | phosphorylase kinase activity | IEA | molecular_function |
| GO:0005975 | carbohydrate metabolic process | TAS | biological_process |
| GO:0016773 | phosphotransferase activity, alcohol group as acce | IEA | molecular_function |
| GO:0019899 | enzyme binding | IEA | molecular_function |
| GO:0016772 | transferase activity, transferring phosphorus-cont | IEA | molecular_function |
| GO:0005978 | glycogen biosynthetic process | IEA | biological_process |
| GO:0009103 | lipopolysaccharide biosynthetic process | IEA | biological_process |
| GO:0005516 | calmodulin binding | IEA | molecular_function |
| GO:0006006 | glucose metabolic process | TAS | biological_process |
| GO:0005980 | glycogen catabolic process | TAS | biological_process |