| UniProt/SwissProt ID: | PDE1A_HUMAN |
| Description: | phosphodiesterase 1A, calmodulin-dependent [Source:HGNC Symbol;Acc:8774] |
| Location: | chr2 q32.1 |
| Node attribute: | PPI(target) |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T202 | VSCLItFAEAL | PhosphoSitePlus | |
| S82 | TEDELsDIQTD | PhosphoSitePlus | |
| S212 | LEVGYsKYKNP | PhosphoSitePlus | |
| Y214 | VGYSKyKNPYH | PhosphoSitePlus | |
| T86 | LSDIQtDSVPS | PhosphoSitePlus | |
| S198 | FKIPVsCLITF | PhosphoSitePlus | |
| T185 | IYELFtRYDLI | PhosphoSitePlus | |
| S416 | TMVAQsQIGFI | PDEase_I | PhosphoSitePlus |
| Y282 | DVAILyNDRSV | HPRD | |
| Y282 | DVAILyNDRSV | PDEase_I | PhosphoSitePlus |
| Dephosphorylation site |
| PDE1A_HUMAN do not have dephosphorylation site. |
| Mutation site |
| PDE1A_HUMAN do not have mutation site. |
| Differential expressed protein |
| PDE1A_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| PDE1A_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| CALL6_HUMAN | PDE1A_HUMAN | other | KEGG |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa00230 | Purine metabolism |
| hsa04742 | Taste transduction |
| hsa05032 | Morphine addiction |
| hsa04020 | Calcium signaling pathway |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0046872 | metal ion binding | IEA | molecular_function |
| GO:0004114 | 3',5'-cyclic-nucleotide phosphodiesterase activity | IEA | molecular_function |
| GO:0008543 | fibroblast growth factor receptor signaling pathwa | TAS | biological_process |
| GO:0048011 | nerve growth factor receptor signaling pathway | TAS | biological_process |
| GO:0005516 | calmodulin binding | IEA | molecular_function |
| GO:0007202 | activation of phospholipase C activity | TAS | biological_process |
| GO:0007596 | blood coagulation | TAS | biological_process |
| GO:0003824 | catalytic activity | IEA | molecular_function |
| GO:0005829 | cytosol | TAS | cellular_component |
| GO:0000042 | protein targeting to Golgi | IEA | biological_process |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0004117 | calmodulin-dependent cyclic-nucleotide phosphodies | TAS | molecular_function |
| GO:0007165 | signal transduction | IEA | biological_process |
| GO:0007165 | signal transduction | TAS | biological_process |
| GO:0007173 | epidermal growth factor receptor signaling pathway | TAS | biological_process |