Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:PCGF6_HUMAN
Description:polycomb group ring finger 6 [Source:HGNC Symbol;Acc:21156]
Location:chr10 q24.33
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S115GGRQDsEDEEEHPRD
S115GGRQDsEDEEEDaxx; BUD22PhosphoSitePlus
S30PPPPVsPPALTPhosphoSitePlus; RegPhos
T284VSGEAtIGHVEPhosphoSitePlus; HPRD
S205KFVRVsGEATIHPRD
S280KFVRVsGEATIPhosphoSitePlus; HPRD
S105DMSHFsLRLEGDaxx; BUD22PhosphoSitePlus
S30PPPPVsPPALTCDK7HPRD; RegPhos
T209VSGEAtIGHVEHPRD
T8GVAVVtAGSVGPhosphoSitePlus

Dephosphorylation site
PCGF6_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000338845R218GCOSMICRenal Cancer
ENSP00000358862R293GCOSMICRenal Cancer

Differential expressed protein
PCGF6_HUMAN is not differential expressed protein.

Hyperphosphorylation site
PCGF6_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
ZAGL2_HUMANPCGF6_HUMANkinase -> substrateRegPhos
CDK7_HUMANPCGF6_HUMANkinase -> substrateHPRD; RegPhos

Function Annotation
KEGG Pathway
PCGF6_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0045892negative regulation of transcription, DNA-dependenIDAbiological_process
GO:0031519PcG protein complexIDAcellular_component
GO:0005515protein bindingIPImolecular_function
GO:0008270zinc ion bindingIEAmolecular_function
GO:0003677DNA bindingIDAmolecular_function
GO:0035102PRC1 complexIDAcellular_component
GO:0003700sequence-specific DNA binding transcription factorIDAmolecular_function
GO:0005634nucleusIEAcellular_component
GO:0005634nucleusIDAcellular_component
GO:0006351transcription, DNA-dependentIEAbiological_process


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