Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:PACA_HUMAN
Description:adenylate cyclase activating polypeptide 1 (pituitary) [Source:HGNC Symbol;Acc:241]
Location:chr18 p11.32
Node attribute:ligand

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S142FTDSYsRYRKQHormone_2PhosphoSitePlus
Y141IFTDSySRYRKHormone_2PhosphoSitePlus
Y162VLGKRyKQRVKPhosphoSitePlus
Y153MAVKKyLAAVLHormone_2PhosphoSitePlus

Dephosphorylation site
PACA_HUMAN do not have dephosphorylation site.

Mutation site
PACA_HUMAN do not have mutation site.

Differential expressed protein
PACA_HUMAN is not differential expressed protein.

Hyperphosphorylation site
PACA_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
PACA_HUMANPACR_HUMANligand -> receptorHPMR
PACA_HUMANVIPR1_HUMANligand -> receptorHPMR

Function Annotation
KEGG Pathway
PACA_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0032880regulation of protein localizationIDAbiological_process
GO:0031858pituitary adenylate cyclase-activating polypeptideIEAmolecular_function
GO:0001821histamine secretionIEAbiological_process
GO:0005576extracellular regionTAScellular_component
GO:0008284positive regulation of cell proliferationIEAbiological_process
GO:0043195terminal buttonIEAcellular_component
GO:0045786negative regulation of cell cycleIEAbiological_process
GO:0032755positive regulation of interleukin-6 productionIEAbiological_process
GO:0070445regulation of oligodendrocyte progenitor proliferaIEAbiological_process
GO:0005102receptor bindingIPImolecular_function
GO:0045471response to ethanolIEAbiological_process
GO:0010579positive regulation of adenylate cyclase activity IDAbiological_process
GO:0001662behavioral fear responseIEAbiological_process
GO:0016521pituitary adenylate cyclase activating polypeptideIEAmolecular_function
GO:0007190activation of adenylate cyclase activityTASbiological_process
GO:0016521pituitary adenylate cyclase activating polypeptideIDAmolecular_function
GO:0043267negative regulation of potassium ion transportIEAbiological_process
GO:0002865negative regulation of acute inflammatory responseIEAbiological_process
GO:0046034ATP metabolic processIEAbiological_process
GO:0007267cell-cell signalingTASbiological_process
GO:0002878negative regulation of acute inflammatory responseIEAbiological_process
GO:0051428peptide hormone receptor bindingIDAmolecular_function
GO:0071385cellular response to glucocorticoid stimulusIEAbiological_process
GO:0045909positive regulation of vasodilationIEAbiological_process
GO:0048011nerve growth factor receptor signaling pathwayTASbiological_process
GO:0060124positive regulation of growth hormone secretionIEAbiological_process
GO:0007169transmembrane receptor protein tyrosine kinase sigTASbiological_process
GO:0019233sensory perception of painIEAbiological_process
GO:0032880regulation of protein localizationIEAbiological_process
GO:0010579positive regulation of adenylate cyclase activity IEAbiological_process
GO:0042594response to starvationIEAbiological_process
GO:0007204elevation of cytosolic calcium ion concentrationIEAbiological_process
GO:0090274positive regulation of somatostatin secretionIEAbiological_process
GO:0021983pituitary gland developmentIEAbiological_process
GO:0005179hormone activityIEAmolecular_function
GO:0060253negative regulation of glial cell proliferationIEAbiological_process
GO:0010976positive regulation of neuron projection developmeIEAbiological_process
GO:0060078regulation of postsynaptic membrane potentialIEAbiological_process
GO:0030819positive regulation of cAMP biosynthetic processIEAbiological_process
GO:0005057receptor signaling protein activityIEAmolecular_function
GO:0005184neuropeptide hormone activityTASmolecular_function
GO:0007565female pregnancyTASbiological_process
GO:0005615extracellular spaceIEAcellular_component
GO:0008277regulation of G-protein coupled receptor protein sIDAbiological_process
GO:0034259negative regulation of Rho GTPase activityIEAbiological_process
GO:0001541ovarian follicle developmentIEAbiological_process
GO:0051968positive regulation of synaptic transmission, glutIEAbiological_process