Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:P5CR1_HUMAN
Description:pyrroline-5-carboxylate reductase 1 [Source:HGNC Symbol;Acc:9721]
Location:chr17 q25.3
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S270TRELQsMADQEPhosphoSitePlus
S233KDNVSsPGGATPhosphoSitePlus; HPRD
S303TALSPsGHTKLPhosphoSitePlus; HPRD
S301AGTALsPSGHTPhosphoSitePlus
S294KVKLDsPAGTAPhosphoSitePlus

Dephosphorylation site
P5CR1_HUMAN do not have dephosphorylation site.

Mutation site
P5CR1_HUMAN do not have mutation site.

Differential expressed protein
P5CR1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
P5CR1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
ANPRB_HUMANP5CR1_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
P5CR1_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0042802identical protein bindingIPImolecular_function
GO:0004735pyrroline-5-carboxylate reductase activityIEAmolecular_function
GO:0008652cellular amino acid biosynthetic processTASbiological_process
GO:0016616oxidoreductase activity, acting on the CH-OH groupIEAmolecular_function
GO:0016491oxidoreductase activityIEAmolecular_function
GO:0005759mitochondrial matrixTAScellular_component
GO:0051287NAD bindingIEAmolecular_function
GO:0000166nucleotide bindingIEAmolecular_function
GO:0006561proline biosynthetic processIEAbiological_process
GO:0034641cellular nitrogen compound metabolic processTASbiological_process
GO:0044281small molecule metabolic processTASbiological_process
GO:0034599cellular response to oxidative stressIMPbiological_process
GO:0005739mitochondrionIEAcellular_component
GO:0055114oxidation-reduction processIEAbiological_process
GO:0046168glycerol-3-phosphate catabolic processIEAbiological_process
GO:0005737cytoplasmIEAcellular_component
GO:0055129L-proline biosynthetic processIEAbiological_process


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