Phosphorylation

Protein information

UniProt/SwissProt ID:	P5CR1_HUMAN
Description:	pyrroline-5-carboxylate reductase 1 [Source:HGNC Symbol;Acc:9721]
Location:	chr17 q25.3
Node attribute:	substrate

Position	PhosphoPeptide	Source
S270	TRELQsMADQE	PhosphoSitePlus
S233	KDNVSsPGGAT	PhosphoSitePlus; HPRD
S303	TALSPsGHTKL	PhosphoSitePlus; HPRD
S301	AGTALsPSGHT	PhosphoSitePlus
S294	KVKLDsPAGTA	PhosphoSitePlus

P5CR1_HUMAN do not have dephosphorylation site.

P5CR1_HUMAN do not have mutation site.

P5CR1_HUMAN is not differential expressed protein.

P5CR1_HUMAN do not have hyperphosphorylation site.

Source	Target	Relationship	Resource
ANPRB_HUMAN	P5CR1_HUMAN	kinase -> substrate	Robert H Newman (2013)

KEGG Pathway

P5CR1_HUMAN is not in KEGG pathway.

Gene Ontology

GO ID	GO_Term	Evidence	Ontology
GO:0042802	identical protein binding	IPI	molecular_function
GO:0004735	pyrroline-5-carboxylate reductase activity	IEA	molecular_function
GO:0008652	cellular amino acid biosynthetic process	TAS	biological_process
GO:0016616	oxidoreductase activity, acting on the CH-OH group	IEA	molecular_function
GO:0016491	oxidoreductase activity	IEA	molecular_function
GO:0005759	mitochondrial matrix	TAS	cellular_component
GO:0051287	NAD binding	IEA	molecular_function
GO:0000166	nucleotide binding	IEA	molecular_function
GO:0006561	proline biosynthetic process	IEA	biological_process
GO:0034641	cellular nitrogen compound metabolic process	TAS	biological_process
GO:0044281	small molecule metabolic process	TAS	biological_process
GO:0034599	cellular response to oxidative stress	IMP	biological_process
GO:0005739	mitochondrion	IEA	cellular_component
GO:0055114	oxidation-reduction process	IEA	biological_process
GO:0046168	glycerol-3-phosphate catabolic process	IEA	biological_process
GO:0005737	cytoplasm	IEA	cellular_component
GO:0055129	L-proline biosynthetic process	IEA	biological_process

Human Phosphorylation Mediated
Signaling Transduction Network