Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:P52K_HUMAN
Description:protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) [Source:HGNC Symbol;Acc:9440]
Location:chr11 q13.5
Node attribute:kinase

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S566QGNLEsQLTSEPhosphoSitePlus
S606ALKCLsLVPSVPhosphoSitePlus
S610LSLVPsVMGQLPhosphoSitePlus
S513FFAAGsLTAVLPhosphoSitePlus
T515AAGSLtAVLHSPhosphoSitePlus
Y330CRGQAyIVSSGPhosphoSitePlus
S595LKDIFsEQHLKPhosphoSitePlus
S579YKETLsVPTVEPhosphoSitePlus
T47DLEDKtPDQLNTHAPPhosphoSitePlus

Dephosphorylation site
P52K_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000260045Y744HCOSMICOvarian Cancer21720365
ENSP00000260045T745RCOSMICPancreatic Cancer21252315
ENSP00000260045R557CCOSMICOvarian Cancer21720365

Differential expressed protein
P52K_HUMAN is not differential expressed protein.

Hyperphosphorylation site
P52K_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
P52K_HUMANIF2A_HUMANkinase -> substrateHPRD

Function Annotation
KEGG Pathway
P52K_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0003677DNA bindingIEAmolecular_function
GO:0003676nucleic acid bindingIEAmolecular_function
GO:0007165signal transductionTASbiological_process
GO:0008285negative regulation of cell proliferationTASbiological_process
GO:0005634nucleusIEAcellular_component
GO:0006950response to stressTASbiological_process
GO:0016301kinase activityIEAmolecular_function
GO:0046872metal ion bindingIEAmolecular_function
GO:0046983protein dimerization activityIEAmolecular_function


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