| UniProt/SwissProt ID: | OGFR_HUMAN |
| Description: | opioid growth factor receptor [Source:HGNC Symbol;Acc:15768] |
| Location: | chr20 q13.33 |
| Node attribute: | receptor |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T478 | SGGAQtLALAG | HPRD; phosphoELM | |
| S382 | LSPKEsKKRKL | PhosphoSitePlus | |
| Y196 | GRAQNyQKRFQ | OGFr_N | PhosphoSitePlus |
| S557 | DEPAEsPSETP | OGFr_III | PhosphoSitePlus |
| S45 | DEDEEsEEPRA | PhosphoSitePlus | |
| S537 | DEPAEsPSETP | OGFr_III | PhosphoSitePlus |
| S315 | VEEEGsPGDPD | PhosphoSitePlus; HPRD; phosphoELM; SysPTM | |
| T325 | DHEAStQGRTC | PhosphoSitePlus | |
| S349 | GPQPRsVEPQD | PhosphoSitePlus; HPRD; phosphoELM; SysPTM | |
| S645 | ETPGPsPAGPT | OGFr_III | PhosphoSitePlus |
| S577 | DEPAEsPSETP | phosphoELM | |
| S517 | EGTPGsPSETP | OGFr_III | PhosphoSitePlus |
| S420 | EGCALsQGSLR | PhosphoSitePlus; HPRD; phosphoELM | |
| T329 | STQGRtCGPEH | PhosphoSitePlus | |
| S484 | LALAGsPAPSG | PhosphoSitePlus; HPRD; phosphoELM; SysPTM | |
| T428 | SLRTGtQEVGG | PhosphoSitePlus; HPRD | |
| S378 | RPEPLsPKESK | PhosphoSitePlus; HPRD; phosphoELM; SysPTM | |
| S324 | PDHEAsTQGRT | PhosphoSitePlus | |
| S361 | GPLERsQGDEA | PhosphoSitePlus; HPRD; phosphoELM | |
| S617 | DEPAEsPSETP | OGFr_III | PhosphoSitePlus |
| Y171 | RLVRAyELMLG | OGFr_N | PhosphoSitePlus |
| S577 | DEPAEsPSETP | OGFr_III | PhosphoSitePlus |
| T426 | QGSLRtGTQEV | PhosphoSitePlus | |
| S637 | DEPAEsPSETP | phosphoELM | |
| S488 | GSPAPsGHPKA | PhosphoSitePlus | |
| S423 | ALSQGsLRTGT | PhosphoSitePlus | |
| Y178 | LMLGFyGIRLE | OGFr_N | PhosphoSitePlus |
| S597 | DEPAEsPSETP | OGFr_III | PhosphoSitePlus |
| S517 | EGTPGsPSETP | HPRD | |
| S637 | DEPAEsPSETP | OGFr_III | PhosphoSitePlus |
| T650 | SPAGPtRDEPA | OGFr_III | PhosphoSitePlus |
| Dephosphorylation site |
| OGFR_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000290291 | E659K | COSMIC | Head and Neck Cancer | 21798893 | ENSP00000290291 | Y121C | COSMIC | Head and Neck Cancer | 21798893 | ENSP00000290291 | S557T | COSMIC | Head and Neck Cancer | 21798893 |
| Differential expressed protein |
| OGFR_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| OGFR_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| PENK_HUMAN | OGFR_HUMAN | ligand -> receptor | HPMR |
| Function Annotation |
| KEGG Pathway |
| OGFR_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0004872 | receptor activity | IEA | molecular_function |
| GO:0016020 | membrane | IEA | cellular_component |
| GO:0001558 | regulation of cell growth | NAS | biological_process |
| GO:0005575 | cellular_component | ND | cellular_component |
| GO:0005737 | cytoplasm | IEA | cellular_component |
| GO:0004985 | opioid receptor activity | NAS | molecular_function |
| GO:0038003 | opioid receptor signaling pathway | NAS | biological_process |
| GO:0005634 | nucleus | IEA | cellular_component |